Purpose: The Cancer Imaging Program of the National Cancer Institute convened a
workshop to assess the current status of hypoxia imaging, to assess what is known about the …

In 2012, cancer affected 14.1 million people worldwide and was responsible for 8.2 million
deaths. The disease predominantly affects aged populations and is one of the leading …

PURPOSE: Tumor hypoxia plays a fundamental role in tumor progression and treatment
resistance. Recent evidence that hypoxia also influences the regulation and transcription of …

Advances in molecular imaging are rapidly changing the paradigm for noninvasive
diagnostic imaging from largely morphologic methods to ones that include both anatomy …

Tumor hypoxia is a well-established biological phenomenon that affects the curability of
solid tumors, regardless of treatment modality. Especially for head and neck cancer patients …

A wide variety of imaging approaches have been developed in the past few decades for
monitoring tumor oxygenation and hypoxia in vivo. In particular, nuclear medicine has seen …

Significance: Most solid tumors contain regions of low oxygenation or hypoxia. Tumor
hypoxia has been associated with a poor clinical outcome and plays a critical role in tumor …

There is a need to measure tumor hypoxia in assessing the aggressiveness of tumor and
predicting the outcome of therapy. A number of invasive and noninvasive techniques have …

Reduced oxygen levels (hypoxia) is one of the most important factors influencing clinical
outcome after radiotherapy. This is primarily because hypoxic cells are resistant to radiation …

Since the initial observations made at the beginning of the last century, it has been
established that solid tumors contain regions of low oxygenation (hypoxia). Tumor cells can …