Lower respiratory tract infections are the leading cause of infectious disease deaths
worldwide and are the fifth leading cause of death overall. This is despite conditions such as …

Introduction: Our knowledge about lower respiratory tract infections (LRTIs) has improved
substantially in the last years, but the management of respiratory infections is still a …

Background Acute and chronic respiratory tract infections are a common cause of
inappropriate antimicrobial prescription. Antimicrobial therapy leads to the development of …

The use of antibiotics in acute exacerbations of chronic bronchitis (AECBs) remains the
subject of controversy despite considerable medical and socioeconomic implications. First …

Recent data suggest that adverse events (AEs) associated with the use of antimicrobial
drugs are a major safety concern, with antibiotics implicated in a significant proportion (∼ …

Acute bronchitis and acute exacerbations of chronic bronchitis, common illnesses
encountered by general and family physicians, account for approximately 14 million …

Widespread, increasing antibiotic resistance amongst the major respiratory pathogens has
compromised traditional therapy of the major infective respiratory syndromes, including …

For many years, a considerable amount of evidence has shown that the overuse of
antibiotics is counterproductive and possibly harmful. Numerous papers in the medical …

Antimicrobial Resistance: Tackling a crisis for the health and wealth of nations. The Review
on Antimicrobial Resistance. Chaired by Jim O'Neill. December 2014. https://amr-review …

Background: The evidence for real-world antibiotic use in treating acute exacerbations of
chronic obstructive pulmonary disease (AECOPD) is insufficient. This study aimed to …