Integrins are heterodimeric cell surface adhesion receptors essential for multicellular life.
They connect cells to the extracellular environment and transduce chemical and mechanical …

The integrin family of transmembrane adhesion receptors is essential for sensing and
adhering to the extracellular environment. Integrins are heterodimers composed of non …

Integrins are heterodimeric transmembrane adhesion receptors that couple the actin
cytoskeleton to the extracellular environment and bidirectionally relay signals across the cell …

Integrin adhesion receptors mediate cell–cell and cell–substratum adhesion and provide a
continuous link for the bidirectional transmission of mechanical force and biochemical …

Integrins are cell adhesion molecules that mediate cell-cell, cell–extracellular matrix, and
cell-pathogen interactions. They play critical roles for the immune system in leukocyte …

Integrin signaling is bidirectional.'Inside-out'signals regulate integrin affinity for adhesive
ligands, and ligand-dependent 'outside-in'signals regulate cellular responses to adhesion …

Integrin cell-adhesion receptors mediate interactions between cells and the extracellular
matrix. Dynamic regulation of integrin adhesive function is termedactivation'orinside …

In their roles as major adhesion receptors, integrins signal across the plasma membrane in
both directions. Recent structural and cell biological data suggest models for how integrins …

Integrins are cell surface adhesion receptors that are essential for the development and
function of multicellular animals. Here we summarize recent findings on the regulation of …

Integrins are an important family of adhesion molecules that were first discovered two
decades ago. Integrins are transmembrane heterodimeric glycoprotein receptors consisting …