A recombination puzzle solved: Role for new DNA repair systems in Helicobacter pylori diversity/persistence

G Wang, RJ Maier - DNA Repair, 2011 - books.google.com
Helicobacter pylori is a gram-negative, slow-growing, microaerophilic, spiral bacterium. It is
one of the most common human gastrointestinal pathogens, infecting almost 50% of the …

Recombination and DNA Repair in Helicobacter pylori

MS Dorer, TH Sessler, NR Salama - Annual review of …, 2011 - annualreviews.org
All organisms have pathways that repair the genome, ensuring their survival and that of their
progeny. But these pathways also serve to diversify the genome, causing changes at the …

[HTML][HTML] Genetic battle between Helicobacter pylori and humans. The mechanism underlying homologous recombination in bacteria, which can infect human cells

K Hanada, Y Yamaoka - Microbes and infection, 2014 - Elsevier
Helicobacter pylori is a gram-negative pathogenic bacterium that colonises the human
stomach. The chronic infection it causes results in peptic ulcers and gastric cancers. H. pylori …

The Remarkable Genetics of Helicobacter pylori

D Falush - Mbio, 2022 - Am Soc Microbiol
The Helicobacter pylori genome is more thoroughly mixed by homologous recombination
than by any other organism that has been investigated, leading to apparent “free …

Helicobacter pylori genome plasticity

DA Baltrus, MJ Blaser, K Guillemin - Microbial Pathogenomics, 2009 - karger.com
Helicobacter pylori, a Gram-negative pathogen associated with ulcers, chronic gastritis, and
gastric cancers, has been a resident of the human stomach since early human history [1] …

Evolution of Helicobacter pylori: the role of recombination

S Suerbaum, M Achtman - Trends in microbiology, 1999 - cell.com
Helicobacter pylori is one of the most common pathogenic bacteria infecting humans. It is
estimated that more than half of the human population is chronically colonized with this …

DNA Damage Triggers Genetic Exchange in Helicobacter pylori

MS Dorer, J Fero, NR Salama - PLoS pathogens, 2010 - journals.plos.org
Many organisms respond to DNA damage by inducing expression of DNA repair genes. We
find that the human stomach pathogen Helicobacter pylori instead induces transcription and …

Mutational diversity in mutY deficient Helicobacter pylori and its effect on adaptation to the gastric environment

R Kinoshita-Daitoku, K Kiga, T Sanada, Y Ogura… - Biochemical and …, 2020 - Elsevier
Helicobacter pylori, a pathogenic bacterium that colonizes in the human stomach, harbors
DNA repair genes to counter the gastric environment during chronic infection. In addition, H …

Characterization of Helicobacter pylori factors that control transformation frequency and integration length during inter‐strain DNA recombination

O Humbert, MS Dorer, NR Salama - Molecular microbiology, 2011 - Wiley Online Library
Helicobacter pylori is a genetically diverse bacterial species, owing in part to its natural
competence for DNA uptake that facilitates recombination between strains. Inter‐strain DNA …

The nucleotide excision repair (NER) system of Helicobacter pylori: Role in mutation prevention and chromosomal import patterns after natural transformation

C Moccia, J Krebes, S Kulick, X Didelot, C Kraft… - BMC microbiology, 2012 - Springer
Background Extensive genetic diversity and rapid allelic diversification are characteristics of
the human gastric pathogen Helicobacter pylori, and are believed to contribute to its ability …