Helicobacter pylori-Induced Host Cell DNA Damage and Genetics of Gastric Cancer Development

S Backert, B Linz, N Tegtmeyer - Helicobacter pylori and Gastric Cancer, 2024 - Springer
Gastric cancer is a very serious and deadly disease worldwide with about one million new
cases every year. Most gastric cancer subtypes are associated with genetic and epigenetic …

[PDF][PDF] Επίπτωση συλλοίμωξης H. pylori και E. coli στους μηχανισμούς επιδιόρθωσης βλαβών του DNA

ΜΓΙ Κλαουδάτου - 2023 - ir.lib.uth.gr
Abstract Helicobacter pylori colonizes approximately 50% of the world's population and it
was the first bacterium to be identified as a carcinogen. Chronic infection with this bacterium …

Genome-wide analysis of chromosomal import patterns after natural transformation of Helicobacter pylori

S Bubendorfer, J Krebes, I Yang, E Hage… - Nature …, 2016 - nature.com
Recombination plays a dominant role in the evolution of the bacterial pathogen Helicobacter
pylori, but its dynamics remain incompletely understood. Here we use an in vitro …

Helicobacter pylori utilizes DNA shuffling to modulate the gastric inflammatory response

KT Pham, W Fischer - Future Microbiology, 2013 - Future Medicine
Evaluation of: Barrozo RM, Cooke CL, Hansen LM et al. Functional plasticity in the type IV
secretion system of Helicobacter pylori. PLoS Pathog. 9 (2), e1003189 (2013). Infections …

Mutations Associated to Antibiotic-Resistant Helicobacter pylori: It Is Time to Validate Sequencing Observations

M Pichon, V Luzarraga, C Burucoa - Journal of Clinical Medicine, 2022 - mdpi.com
H. pylori, a Gram-negative microaerophilic microorganism, is the only bacterial pathogen
classified as a Class I carcinogen, due to its association, since its initial discovery, with …

Helicobacter pylori evolution and phenotypic diversification in a changing host

S Suerbaum, C Josenhans - Nature reviews microbiology, 2007 - nature.com
Helicobacter pylori colonizes the stomachs of more than 50% of the world's population,
making it one of the most successful of all human pathogens. One striking characteristic of H …

Restriction of DNA encoding selectable markers decreases the transformation efficiency of Helicobacter pylori

RJ Gorrell, J Yang, JG Kusters… - FEMS Immunology & …, 2005 - academic.oup.com
Helicobacter pylori populations recovered from the human stomach display extensive
recombination and quasispecies development, and this suggests frequent exchange of DNA …

Effect of Host Species on RecG Phenotypes in Helicobacter pylori and Escherichia coli

J Kang, D Tavakoli, A Tschumi, RA Aras… - Journal of …, 2004 - Am Soc Microbiol
Recombination is a fundamental mechanism for the generation of genetic variation.
Helicobacter pylori strains have different frequencies of intragenomic recombination, arising …

Chronic Helicobacter pylori Infection and DNA-Damaged Stem Cells: A Recipe for Disaster

RM Peek Jr - Digestive diseases and sciences, 2013 - Springer
Helicobacter pylori is the most common bacterial infection worldwide. Biological costs
incurred by chronic colonization include increased risk for gastric adenocarcinoma [1] …

Inflammation, DNA Damage, Helicobacter pylori and Gastric Tumorigenesis

P Kalisperati, E Spanou, IS Pateras… - Frontiers in …, 2017 - frontiersin.org
Helicobacter pylori (H. pylori) is a Gram negative bacterium that colonizes the stomach of
almost half human population. It has evolved to escape immune surveillance, establishes …