[引用][C] Is your stomach bugging you?: The rise and fall of the bacterium H. pylori

D Christensen - Science News, 1999 - Wiley Online Library
By DAMARIS CHRISTENSEN he chapter of medicine that describes the bacterium
Helicobacter T pylon is a tale of a few individuals taking a stand against the medical wisdom …

Pathogenesis of Helicobacter pylori Infection

AC Costa, C Figueiredo, E Touati - Helicobacter, 2009 - Wiley Online Library
Helicobacter pylori induces chronic inflammation of the gastric mucosa, but only a proportion
of infected individuals develop peptic ulcer disease or gastric carcinoma. Reasons …

Genomic evolution and transmission of Helicobacter pylori in two South African families

X Didelot, S Nell, I Yang, S Woltemate… - Proceedings of the …, 2013 - National Acad Sciences
Helicobacter pylori infects the stomachs of one in two humans and can cause sequelae that
include ulcers and cancer. Here we sequenced the genomes of 97 H. pylori isolates from 52 …

When bacteria become mutagenic and carcinogenic: lessons from H. pylori

E Touati - Mutation Research/Genetic Toxicology and …, 2010 - Elsevier
More and more convincing data link bacteria to the development of cancers. How bacteria
act as mutagens by altering host genomes, what are the different strategies they develop …

Who's winning the war? Molecular mechanisms of antibiotic resistance in Helicobacter pylori

KR Jones, JH Cha, DS Merrell - Current drug therapy, 2008 - ingentaconnect.com
The ability of clinicians to wage an effective war against many bacterial infections is
increasingly being hampered by skyrocketing rates of antibiotic resistance. Indeed, antibiotic …

The role of genome diversity and immune evasion in persistent infection with Helicobacter pylori

CL Cooke, JL Huff, JV Solnick - FEMS Immunology & Medical …, 2005 - academic.oup.com
Helicobacter pylori is an important human pathogen that chronically colonizes the stomach
of half the world's population. Infection typically occurs in childhood and persists for …

Environmental determinants of transformation efficiency in Helicobacter pylori

ME Moore, A Lam, S Bhatnagar… - Journal of bacteriology, 2014 - Am Soc Microbiol
Helicobacter pylori uses natural competence and homologous recombination to adapt to the
dynamic environment of the stomach mucosa and maintain chronic colonization. Although …

The Helicobacter pylori mutY homologue HP0142 is an antimutator gene that prevents specific C to A transversions

S Kulick, C Moccia, C Kraft, S Suerbaum - Archives of microbiology, 2008 - Springer
Extensive genetic variability resulting from a high mutation rate and frequent recombination
is a characteristic of Helicobacter pylori. Its average mutation rate is 1× 10− 6, similar to that …

Demonstration and Characterization of Mutations Induced by Helicobacter pylori Organisms in Gastric Epithelial Cells

Y Yao, H Tao, DI Park, JL Sepulveda… - …, 2006 - Wiley Online Library
Background: Helicobacter pylori gastritis increases gastric cancer risk. Microsatellite
instability‐type mutations are secondary to deficient DNA mismatch repair. H. pylori gastritis …

Diagnosis of Helicobacter pylori recurrence: relapse or reinfection? Usefulness of molecular tools

J Raymond, JM Thiberge, C Dauga - Scandinavian journal of …, 2016 - Taylor & Francis
Background and aims Infection due to Helicobacter pylori causes many gastrointestinal
diseases including peptic ulcers and gastric carcinoma. Their treatment and prevention …