About half of all episodes of venous thromboembolism (VTE, ie deep vein thrombosis and
pulmonary embolism) are elicited by an acquired clinical risk factor, such as recent surgery …

Thrombophilia is generally defined as an inherited disorder of the hemostatic system that
results in an increased risk of venous thromboembolism (VTE). There are several well …

Unlike the deficiencies of the anticoagulant proteins antithrombin, protein C and S, rare in
patients with venous thromboembolism (VTE; 5% altogether) and in the general population …

BACKGROUND AND OBJECTIVES: In recent years knowledge concerning inherited and
acquired causes of thrombophilia has increased greatly. The most common inherited traits …

The clinical penetrance of venous thromboembolism (VTE) susceptibility genes is variable,
being lower in heterozygous carriers of factor V Leiden and prothrombin 20210A (mild …

Thrombophilias are hereditary and/or acquired conditions that predispose patients to
thrombosis. Testing for thrombophilia is commonly performed in patients with venous …

Despite knowledge of various inherited risk factors associated with venous
thromboembolism (VTE), no definite cause can be found in about 50% of patients. The lack …

In the past decades, the recognition of several inherited thrombophilic traits has greatly
improved our knowledge of the pathogenesis of venous thromboembolism, explaining about …

In the last decades, the knowledge on the etiology of venous thromboembolism (VTE) has
increased tremendously. In approximately half of patients presenting with VTE, one or more …

Inherited thrombophilia, defined as a genetically determined tendency to develop venous
thromboembolism (VTE), contributes to the pathogenesis of~ 40% of VTE episodes. About …