[HTML][HTML] Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation
Glucose is a universal bioenergy source; however, its role in controlling protein interactions
is unappreciated, as are its actions during differentiation-associated intracellular glucose …
is unappreciated, as are its actions during differentiation-associated intracellular glucose …
[HTML][HTML] DDX6 helicase behavior and protein partners in human adipose tissue-derived stem cells during early adipogenesis and osteogenesis
BH Marcon, CK Rebelatto, AR Cofré… - International Journal of …, 2020 - mdpi.com
DDX6 helicase is an RNA-binding protein involved in different aspects of gene expression
regulation. The roles played by DDX6 depend on the complexes associated with it. Here, for …
regulation. The roles played by DDX6 depend on the complexes associated with it. Here, for …
[HTML][HTML] RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation
E Dardenne, MP Espinoza, L Fattet, S Germann… - Cell reports, 2014 - cell.com
The RNA helicases DDX5 and DDX17 are members of a large family of highly conserved
proteins that are involved in gene-expression regulation; however, their in vivo targets and …
proteins that are involved in gene-expression regulation; however, their in vivo targets and …
DDX39B promotes translation through regulation of pre-ribosomal RNA levels
ABSTRACT DDX39B, a DExD RNA helicase, is known to be involved in various cellular
processes such as mRNA export, splicing and translation. Previous studies showed that the …
processes such as mRNA export, splicing and translation. Previous studies showed that the …
RNA helicase DDX21 mediates nucleotide stress responses in neural crest and melanoma cells
The availability of nucleotides has a direct impact on transcription. The inhibition of
dihydroorotate dehydrogenase (DHODH) with leflunomide impacts nucleotide pools by …
dihydroorotate dehydrogenase (DHODH) with leflunomide impacts nucleotide pools by …
DDX49 is an RNA helicase that affects translation by regulating mRNA export and the levels of pre-ribosomal RNA
Among the proteins predicted to be a part of the DExD box RNA helicase family, the
functions of DDX49 are unknown. Here, we characterize the enzymatic activities and …
functions of DDX49 are unknown. Here, we characterize the enzymatic activities and …
[HTML][HTML] The human DEAD-box helicase DDX3X as a regulator of mRNA translation
CS Ryan, M Schröder - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
The human DEAD-box protein DDX3X is an RNA remodelling enzyme that has been
implicated in various aspects of RNA metabolism. In addition, like many DEAD-box proteins …
implicated in various aspects of RNA metabolism. In addition, like many DEAD-box proteins …
Human DDX3 functions in translation and interacts with the translation initiation factor eIF3
CS Lee, AP Dias, M Jedrychowski, AH Patel… - Nucleic acids …, 2008 - academic.oup.com
The conserved RNA helicase DDX3 is of major medical importance due to its involvement in
numerous cancers, human hepatitis C virus (HCV) and HIV. Although DDX3 has been …
numerous cancers, human hepatitis C virus (HCV) and HIV. Although DDX3 has been …
DDX3X and DDX3Y are redundant in protein synthesis
DDX3 is a DEAD-box RNA helicase that regulates translation and is encoded by the X-and
Y-linked paralogs DDX3X and DDX3Y. While DDX3X is ubiquitously expressed in human …
Y-linked paralogs DDX3X and DDX3Y. While DDX3X is ubiquitously expressed in human …
The current understanding of Ded1p/DDX3 homologs from yeast to human
WY Tarn, TH Chang - RNA biology, 2009 - Taylor & Francis
DExD/H-box RNA helicases are involved in almost all steps of the eukaryotic mRNA
biogenesis. The DEAD-box protein Ded1p/DDX3 is conserved from yeast to human. Various …
biogenesis. The DEAD-box protein Ded1p/DDX3 is conserved from yeast to human. Various …