Role of methionine adenosyltransferase 2A in bovine preimplantation development and its associated genomic regions
S Ikeda, R Kawahara-Miki, H Iwata, M Sugimoto… - Scientific reports, 2017 - nature.com
Methionine adenosyltransferase (MAT) is involved in folate-mediated one-carbon
metabolism, which is essential for preimplantation embryos in terms of both short-term …
metabolism, which is essential for preimplantation embryos in terms of both short-term …
MAT2A is Essential for Zygotic Genome Activation by Maintaining of Histone Methylation in Porcine Embryos
XH Li, SH Lee, QY Lu, CL Zhan, GH Lee, JD Kim… - Theriogenology, 2024 - Elsevier
Abstract Methionine adenosyltransferase 2A (MAT2A) is an essential enzyme in the
methionine cycle that generates S-adenosylmethionine (SAM) by reacting with methionine …
methionine cycle that generates S-adenosylmethionine (SAM) by reacting with methionine …
Methionine adenosyltransferase 2A regulates mouse zygotic genome activation and morula to blastocyst transition
H Sun, J Kang, J Su, J Zhang, L Zhang… - Biology of …, 2019 - academic.oup.com
Abstract Methionine adenosyltransferase II (MAT2A) is essential to the synthesis of S-
adenosylmethionine, a major methyl donor, from L-methionine and ATP. Upon fertilization …
adenosylmethionine, a major methyl donor, from L-methionine and ATP. Upon fertilization …
Importance of methionine metabolism in morula-to-blastocyst transition in bovine preimplantation embryos
S Ikeda, M Sugimoto, S Kume - Journal of Reproduction and …, 2012 - jstage.jst.go.jp
The roles of methionine metabolism in bovine preimplantation embryo development were
investigated by using ethionine, an antimetabolite of methionine. In vitro produced bovine …
investigated by using ethionine, an antimetabolite of methionine. In vitro produced bovine …
CBS and MAT2A improve methionine‐mediated DNA synthesis through SAMTOR/mTORC1/S6K1/CAD pathway during embryo implantation
S Cai, Q Ye, X Zeng, G Yang, C Ye, M Chen… - Cell …, 2021 - Wiley Online Library
Objectives Early pregnancy loss is a major clinical concern in animal and human
reproduction, which is largely influenced by embryo implantation. The importance of …
reproduction, which is largely influenced by embryo implantation. The importance of …
Effect of maternal methionine supplementation on the transcriptome of bovine preimplantation embryos
F Peñagaricano, AH Souza, PD Carvalho, AM Driver… - PloS one, 2013 - journals.plos.org
Maternal nutrition exclusively during the periconceptional period can induce remarkable
effects on both oocyte maturation and early embryo development, which in turn can have …
effects on both oocyte maturation and early embryo development, which in turn can have …
Responses of bovine early embryos to S-adenosyl methionine supplementation in culture
HA Shojaei Saadi, D Gagné, É Fournier… - …, 2016 - Taylor & Francis
Aim: There is a growing concern about the potential adverse effects of high dose folic acid
(FA) supplementation before and during pregnancy. FA metabolism generates S-adenosyl …
(FA) supplementation before and during pregnancy. FA metabolism generates S-adenosyl …
Methionine adenosyltransferase 2β participates in mouse oocyte maturation by regulating the MAPK pathway
Q An, H Sun, J Zhang, Z Lu, W Peng, S Xu… - Reproductive …, 2020 - Springer
The methionine adenosyltransferase 2β gene (Mat2b) encodes for the regulatory subunit of
methionine adenosyltransferase (MAT), which catalyzes the biosynthesis of S …
methionine adenosyltransferase (MAT), which catalyzes the biosynthesis of S …
Human embryonic stem cell methyl cycle enzyme expression: modelling epigenetic programming in assisted reproduction?
W Steele, C Allegrucci, R Singh, E Lucas… - Reproductive …, 2005 - Elsevier
To investigate a possible mechanism for inducing epigenetic defects in the preimplantation
embryo, a human embryonic stem cell model was developed, and gene expression of the …
embryo, a human embryonic stem cell model was developed, and gene expression of the …
Ddit3 regulates key enzymes in the methionine cycle and flux during embryonic development
S Cai, S Quan, G Yang, X Zeng, X Wang, C Ye… - The Journal of …, 2023 - Elsevier
One-carbon metabolism is a key metabolic network that integrates nutritional signals with
embryonic development. However, the response of one-carbon metabolism to methionine …
embryonic development. However, the response of one-carbon metabolism to methionine …