Folate is essential for DNA synthesis and methylation via one‐carbon (C1) metabolism
during embryonic development. It is transported into the developing oocytes via folate …

Abstract N6-methyladenosine (m6A) plays a key role in mammalian early embryonic
development and cell lineage differentiation. However, the role and mechanisms of 18S …

Background Embryonic genome activation (EGA) is a critical event for the preimplantation
embryo, which is manifested by changes in chromatin structure, transcriptional machinery …

TRPM7 (transient receptor potential cation channel subfamily M member 7) is a chanzyme
with channel and kinase domains essential for embryo development. Using gamete-specific …

Litter size is one of the most economically important traits in commercial pig farming. It has
been estimated that approximately 30% of porcine embryos are lost during the peri …

Epigenetic modifications play critical roles during somatic cell nuclear transfer (SCNT)
embryo development. Whether RNA N6‐methyladenosine (m6A) affects the developmental …

Vitamin C is not only an antioxidant but also a regulator of epigenetic modifications that can
enhance the activity of the ten‐eleven translocation (TET) family dioxygenases and promote …

Embryonic diapause in mammals leads to a reversible developmental arrest. While
completely halted in many species, European roe deer (Capreolus capreolus) embryos …

To further optimize the culturing of preimplantation embryos, we undertook metabolomic
analysis of relevant culture media using capillary electrophoresis time-of-flight mass …

Reproductive efficiency is critically dependent on embryo survival, establishment of a
successful pregnancy and placental development. Recent advances in gene editing …