Understanding preimplantation embryonic development is crucial for the improvement of
assisted reproductive technologies and animal production. To achieve this goal, it is …

Development of placental folds is a critical event affecting placental function in pigs because
it can increase surface area for improvement in capillary density as gestation advances …

Bovine preimplantation embryos exhibit dramatic biological changes between before and
after the 8-16-cell stage. Here we report a simple lipofection method to transfect siRNA into …

DNA methylation is a central epigenetic event that regulates cellular differentiation,
reprogramming, and pathogenesis. DNA demethylation occurs in preimplantation embryos …

Bovine embryos can be generated by in vitro fertilization or somatic nuclear transfer;
however, these differ from their in vivo counterparts in many aspects and exhibit a higher …

Pig cloning by somatic cell nuclear transfer (SCNT) frequently undergoes incomplete
epigenetic remodeling during the maternal-to-zygotic transition, which leads to a significant …

Efficient epigenetic reprogramming is crucial for the in vitro development of mammalian
somatic cell nuclear transfer (SCNT) embryos. The aberrant levels of histone H3 lysine 9 …

Most in vitro culture conditions are less‐than‐optimal for embryo development. Here, we
used a transcriptional‐profiling database to identify culture‐induced differences in gene …

Extensive epigenetic reprogramming occurs during preimplantation embryonic
development. However, the impact of DNA methylation in plateau yak preimplantation …

Abstract The TET (Ten-Eleven Translocation) proteins catalyze the oxidation of 5mC (5-
methylcytosine) to 5hmC (5-hydroxymethylcytosine) and play crucial roles in embryonic …