Unleashing the efficacy of immune checkpoint inhibitors for advanced hepatocellular carcinoma: factors, strategies, and ongoing trials
J Yu, M Li, B Ren, L Cheng, X Wang, Z Ma… - Frontiers in …, 2023 - frontiersin.org
Hepatocellular carcinoma (HCC) is a prevalent primary liver cancer, representing
approximately 85% of cases. The diagnosis is often made in the middle and late stages …
approximately 85% of cases. The diagnosis is often made in the middle and late stages …
Current landscape of immune checkpoint inhibitor therapy for hepatocellular carcinoma
Simple Summary Hepatocellular carcinoma (HCC) is the most common primary hepatic
malignancy, with increasing incidence over the past several decades. The majority of …
malignancy, with increasing incidence over the past several decades. The majority of …
Immune checkpoint inhibitors in the treatment of hepatocellular carcinoma
Despite advances in cancer treatment, hepatocellular carcinoma (HCC), the most common
form of liver cancer, remains a major public health problem worldwide. The immune …
form of liver cancer, remains a major public health problem worldwide. The immune …
Immune checkpoint inhibitors for advanced hepatocellular carcinoma: Monotherapies and combined therapies
T Ouyang, X Kan, C Zheng - Frontiers in oncology, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is an important cause of cancer death and is considered
the 3rd most lethal around the world. Hepatectomy, liver transplantation, and ablation …
the 3rd most lethal around the world. Hepatectomy, liver transplantation, and ablation …
[HTML][HTML] Treatment of advanced hepatocellular carcinoma: immunotherapy from checkpoint blockade to potential of cellular treatment
The absence of potent therapeutic option accounts for the dismal prognosis of advanced
hepatocellular carcinoma (HCC) with high mortality and recurrence rate. For a decade …
hepatocellular carcinoma (HCC) with high mortality and recurrence rate. For a decade …
Lessons from immune checkpoint inhibitor trials in hepatocellular carcinoma
R Mohr, F Jost-Brinkmann, B Özdirik… - Frontiers in …, 2021 - frontiersin.org
The implementation of immune checkpoint inhibitors (ICI) into the clinical management of
different malignancies has largely changed our understanding of cancer treatment. After …
different malignancies has largely changed our understanding of cancer treatment. After …
First-line immune checkpoint inhibitor-based combinations in unresectable hepatocellular carcinoma: current management and future challenges
A Rizzo, AD Ricci, G Gadaleta-Caldarola… - Expert Review of …, 2021 - Taylor & Francis
Introduction Immunotherapy has recently taken on an extremely important role in medical
oncology, as first-or later-line treatment in several tumor types, and recent years have seen …
oncology, as first-or later-line treatment in several tumor types, and recent years have seen …
Cure the incurable? Recent breakthroughs in immune checkpoint blockade for hepatocellular carcinoma
Simple Summary Liver cancer is one of the most devastating human malignancies
worldwide, especially in Asia, where over 70% of new cases are diagnosed. Most liver …
worldwide, especially in Asia, where over 70% of new cases are diagnosed. Most liver …
Immunotherapy updates in advanced hepatocellular carcinoma
A Singh, RJ Beechinor, JC Huynh, D Li, F Dayyani… - Cancers, 2021 - mdpi.com
Simple Summary Advanced hepatocellular carcinoma (HCC) carries a grim prognosis,
which has historically been compounded by a lack of available systemic therapies …
which has historically been compounded by a lack of available systemic therapies …
Combination of molecularly targeted therapies and immune checkpoint inhibitors in the new era of unresectable hepatocellular carcinoma treatment
ZL Liu, JH Liu, D Staiculescu… - Therapeutic Advances in …, 2021 - journals.sagepub.com
Multikinase inhibitors (MKIs) have been the only first-line treatment for advanced
hepatocellular carcinoma (HCC) for more than a decade, until the approval of immune …
hepatocellular carcinoma (HCC) for more than a decade, until the approval of immune …