[HTML][HTML] Drugs in Cyclodextrin in Liposomes: How a Suitable Formulation of an Active Substance Can Improve Its Efficiency?

G Levet, S Krykun, B Cornelio, S Pilato, S Moffa… - Processes, 2024 - mdpi.com
The design of new drug delivery systems has been widely sought after. The stability,
solubility, and difficulty of targeting active sites for new drugs have always been challenging …

Liposomes incorporating cyclodextrin–drug inclusion complexes: Current state of knowledge

R Gharib, H Greige-Gerges, S Fourmentin… - Carbohydrate …, 2015 - Elsevier
Cyclodextrins (CDs) are cyclic oligosaccharides, consisting of glucopyranose units, which
are able to form host–guest inclusion complexes with lipophilic molecules. The ability of CD …

Drug-in-cyclodextrin-in-liposomes: A promising delivery system for hydrophobic drugs

J Chen, WL Lu, W Gu, SS Lu, ZP Chen… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Recently, the entrapment of hydrophobic drugs in the form of water-soluble
drug–cyclodextrin (CD) complex in liposomes has been investigated as a new strategy to …

Cyclodextrins in drug delivery

N Erdoğar, E Bilensoy - Nanotechnology and Drug Delivery …, 2014 - api.taylorfrancis.com
Cyclodextrins have been widely applied to the pharmaceutical field due to their ability to
include hydrophobic molecules in their cavity and to mask certain physicochemical …

[HTML][HTML] Effect of the incorporation of functionalized cyclodextrins in the liposomal bilayer

R Zappacosta, B Cornelio, S Pilato, G Siani, F Estour… - Molecules, 2019 - mdpi.com
Liposomes loaded with drug–cyclodextrin complexes are widely used as drug delivery
systems, especially for species with low aqueous solubility and stability. Investigation of the …

Advantages of the combined use of cyclodextrins and nanocarriers in drug delivery: A review

P Mura - International journal of pharmaceutics, 2020 - Elsevier
Complexation with cyclodextrins (CDs) has been widely and successfully used in
pharmaceutical field, mainly for enhancing solubility, stability and bioavailability of a variety …

Entrapment of cyclodextrin-drug complexes into liposomes: potential advantages in drug delivery

B McCormack, G Gregoriadis - Journal of drug targeting, 1994 - Taylor & Francis
A novel concept in drug delivery discussed here, takes advantage of certain properties of the
drug “containers” cyclodextrins and liposomes to combine them into a single system thus …

Preparation of hydroxypropyl-β-cyclodextrin-incorporated liposomes and evaluation of their rapid release property

H Lim, S Jin, Y Jeong, SB Kim, DJ Jang… - Journal of Industrial and …, 2021 - Elsevier
The aim of this study was to investigate the effect of hydroxypropyl-β-cyclodextrin (HPβCD),
widely used as a solubility enhancer, on liposomal formulations. To this end, HPβCD was …

Cyclodextrins in targeting: application to nanoparticles

D Duchêne, G Ponchel, D Wouessidjewe - Advanced drug delivery reviews, 1999 - Elsevier
For some years cyclodextrins and their hydrophilic derivatives have been described in the
literature as solubilizers capable of enhancing the loading capacity of liposomes and …

Cyclodextrin-membrane interaction in drug delivery and membrane structure maintenance

Z Hammoud, N Khreich, L Auezova… - International journal of …, 2019 - Elsevier
Cyclodextrins (CDs) are cyclic oligosaccharides able to improve drug water solubility and
stability by forming CD/drug inclusion complexes. To further increase drug entrapment and …