Emerging biologic therapies in rheumatoid arthritis: cell ta... : Current Opinion in Rheumatology
Emerging biologic therapies in rheumatoid arthritis: cell targets and cytokines : Current …

IL-17 produced by Th17 cells has been implicated in the pathogenesis of rheumatoid
arthritis (RA). It is important to prevent the differentiation of Th17 cells in RA. Homodimeric …

Despite major progress in the treatment of rheumatoid arthritis (RA), strong unmet medical
need remains, as only a minor proportion of patients reach sustained clinical remission. New …

Objective Previous work has suggested that the granulocyte macrophage colony stimulating
factor (GM-CSF)–GM-CSF receptor α axis (GM-CSFRα) may provide a new therapeutic …

Background To identify biomarkers for guiding therapy and predicting clinical response of
Tripterysium Glycosides Tablets (TGT) treatment is an urgent task due to individual …

Inflammatory arthritis is a cluster of diseases caused by unregulated activity of the immune
system. The lost homeostasis is followed by the immune attack of one's self, what damages …

GPCRs arguably represent the most effective current therapeutic targets for a plethora of
diseases. GPCRs also possess a pivotal role in the regulation of the physiological balance …

Regulation of angiogenesis occurs in the context of particular microenvironments and is
governed by a sensitive balance between angiogenic and anti-angiogenic mediators. Under …

Rheumatoid arthritis (RA) is the most common inflammatory rheumatic disease. It leads to
irreversible joint damage, physical handicap, and reduced life expectancy. The past two …

Chronic inflammation is implicated in numerous human pathologies. In particular, low-grade
inflammation is currently recognized as an important mechanism of osteoarthritis (OA), at …