Cortisol regulates adipose tissue differentiation, function, and distribution. In excess, cortisol
causes visceral obesity. Visceral obesity is one of the key components of the metabolic …

Background Although there is substantial evidence of differential hypothalamic-pituitary-
adrenal (HPA) axis activity in both generalized and abdominal obesity, consistent trends in …

The understanding of how adrenal function is challenged by the interplay of our genetic and
environmental milieu has highlighted the importance of inappropriate cortisol regulation in …

Obesity constitutes one of the most serious public health problems, with rapidly increasing
prevalence in western societies. Consequently, metabolic syndrome, a condition strongly …

Context: The metabolic syndrome (MetS) is a cluster of metabolic abnormalities that
increase the risk for type 2 diabetes mellitus and vascular disease. The common …

A hypothetical role of glucocorticoids in human obesity has been suggested since the
abdominal obesity phenotype and syndromes of endogenous or exogenous …

Excess body fat, obesity, is one of the most common disorders in clinical practice. In
addition, there is a clustering of several risk factors with obesity, including hypertension …

In clinical practice, a considerable overlap can be observed between the sequelae of
obesity and an excess of glucocorticoids (ie, Cushing's syndrome). In Cushing's, all aspects …

Increasing evidence suggests that activation of the hypothalamic-pituitary-adrenal (HPA)
axis may contribute to the pathogenesis of the metabolic syndrome and obesity. The …

A number of studies have suggested that the metabolic syndrome (principally, the
combination of hypertension, glucose intolerance, and dyslipidemia) is associated with …