Targeting and differentiating stem cells at sites of injury and repair is an exciting and
promising area for disease treatment and reparative medicine. We have investigated remote …

Mechanical cues are employed to promote stem cell differentiation and functional tissue
formation in tissue engineering and regenerative medicine. We have developed a Magnetic …

Bone requires dynamic mechanical stimulation to form and maintain functional tissue, yet
mechanical stimuli are often lacking in many therapeutic approaches for bone regeneration …

Magnetic ion channel activation technology uses superparamagnetic nanoparticles
conjugated with targeting antibodies to apply mechanical force directly to stretch-activated …

Chondrogenic commitments of mesenchymal stem cells (MSCs) require 3D cellular
organization. Furthermore, recent progresses in bioreactor technology have contributed to …

Mechanical signalling plays a pivotal role in maintaining bone cell function and remodelling
of the skeleton. Our previous work has highlighted the potential role of mechano-induction in …

Magnetic particles were coated with RGD and adhered to primary human osteoblasts.
During a 21-day culture, the osteoblasts plus adhered magnetic particles underwent a daily …

Tissue-engineering strategies for the treatment of osteoarthritis would benefit from the ability
to induce chondrogenesis in precursor cells. One such cell source is bone marrow-derived …

The role of biomechanical stimuli, or mechanotransduction, in normal bone homeostasis
and repair is understood to facilitate effective osteogenesis of mesenchymal stem cells …

Functional biomaterials with magnetic properties are considerably useful for regulating cell
behavior and promoting bone regeneration. And the combination of such biomaterials with …