Prevalence of obesity in the general population has increased in the past 15 years from 15%
to 35%. With increasing obesity, the coincident medical and social consequences are …

Objective: To investigate whether dietary restraint, a landmark of successful dieting, is
associated with specific patterns of brain responses to the sensory experience of food and …

Natural rewards, such as food and social interaction, as well as drugs of abuse elicit
increased mesolimbic dopamine release in the nucleus accumbens (NAc). Drugs of abuse …

Obesity is associated with physical inactivity, which exacerbates the health consequences of
weight gain. However, the mechanisms that mediate this association are unknown. We …

Food intake is mediated, in part, through brain pathways for motivation and reinforcement.
Dysregulation of these pathways may underlay some of the behaviors exhibited by patients …

The drive for food is one of the most powerful of human and animal behaviors. Dopamine, a
neurotransmitter involved with motivation and reward, its believed to regulate food intake in …

Drugs and food exert their reinforcing effects in part by increasing dopamine (DA) in limbic
regions, which has generated interest in understanding how drug abuse/addiction relates to …

Alterations in dopaminergic circuitry play a critical role in food reward and may contribute to
susceptibility to obesity. Ingestion of sweets releases dopamine in striatum, and both sweet …

Dopamine (DA) neurons in the ventral tegmental area (VTA) are heterogeneous and
differentially regulate ingestive and locomotor behaviors that affect energy balance …

The aim of this review is to explore how metabolic changes induced by diets high in
saturated fat (HFD) affect nucleus accumbens (NAc) dopamine neurotransmission and food …