Background We assessed the impact of an evidence-based neuroprotection care bundle on
the risk of brain injury in extremely preterm infants. Methods We implemented a …

Improving neurodevelopmental outcome for preterm infants is an important challenge for
neonatal medicine. The disruption of normal brain growth and neurological development is …

OBJECTIVE: To determine early predictors of abnormal outcome at≥ 24 months' age in
neonates at risk for hypoxic–ischemic brain injury. STUDY DESIGN: A prospective cohort …

Importance Interventions to reduce severe brain injury risk are the prime focus in neonatal
clinical trials. Objective To evaluate multiple perinatal interventions across clinical settings …

Neonatal neurocritical care is an evolving subsubspecialty whose goal is to implement
neuroprotective care strategies, continuous bedside monitoring of neurologic function, and …

Infants born at≤ 32+ 6 weeks gestation are at higher risk for intracranial ischemic and
hemorrhagic injuries, which often occur in the first 72 hours postbirth. Antenatal strategies to …

In recent decades, advances in maternal-fetal, obstetrics, and neonatal medicine have led to
the increased survival of preterm infants. Very preterm infants (< 32 weeks gestation), who …

AMONG THE 500 000 infants born prematurely in 2003 in the United States, 79 000 were
born very prematurely. 1–3 These very premature infants, defined as having been born …

Advances in neonatology have led to unprecedented improvements in neonatal survival
such that those born as early as 22 weeks of gestation now have some chance of survival …

Preterm birth interrupts the precise process of fetal maturation, forcing critical neurologic
growth to continue within the Neonatal Intensive Care Unit (NICU). Concern for the impact of …