New techniques for individualized assessment of white matter integrity are needed to detect
traumatic axonal injury (TAI) and predict outcomes in critically ill patients with acute severe …

There is an urgent, unmet demand for definitive biological diagnosis of traumatic brain injury
(TBI) to pinpoint the location and extent of damage. We have developed High-Definition …

We seek to elucidate the underlying pathophysiology of injury sustained after mild traumatic
brain injury (mTBI) using multi-shell diffusion magnetic resonance imaging, deriving …

Poor outcomes after traumatic brain injury (TBI) are common yet remain difficult to predict.
Diffuse axonal injury is important for outcomes, but its assessment remains limited in the …

Traumatic axonal injury (TAI) contributes significantly to mortality and morbidity after
traumatic brain injury (TBI), but its identification is still a diagnostic challenge because of the …

Conventional clinical neuroimaging is insensitive to axonal injury in traumatic brain injury
(TBI). Immunocytochemical staining reveals changes to axonal morphology within hours …

Diffusion tractography magnetic resonance imaging (MRI) can infer changes in network
connectivity in patients with traumatic brain injury (TBI), but the pathological substrates of …

To identify and characterize otherwise occult inter-individual spatial variation of white matter
abnormalities across mild traumatic brain injury (mTBI) patients. After informed consent and …

Diffusion tensor imaging (DTI) has been useful in showing compromise after traumatic
axonal injury (TAI) at the chronic stage; however, white matter (WM) compromise from acute …

Patients with traumatic brain injuries (TBI), especially those with chronic health symptoms,
often experience behavioral impairments attributable to white matter (WM) microstructural …