Fucoxanthin inhibits the inflammation response in paw edema model through suppressing MAPKs, Akt, and NFκB

JH Choi, NH Kim, SJ Kim, HJ Lee… - Journal of Biochemical …, 2016 - Wiley Online Library
Undaria pinnatifida is a well‐known traditional Korean food with a variety of biological
activities. Carrageenan (carr) is commonly used to induce paw edema in animal models …

Fucoxanthin inhibits the inflammatory response by suppressing the activation of NF-κB and MAPKs in lipopolysaccharide-induced RAW 264.7 macrophages

KN Kim, SJ Heo, WJ Yoon, SM Kang, G Ahn… - European journal of …, 2010 - Elsevier
It has been previously determined that pro-inflammatory mediators including nitric oxide
(NO), prostaglandin E2 (PGE2), tumor necrosis factor (TNF)-α, and interleukin (IL)-1β and IL …

Anti-neuroinflammatory effects of fucoxanthin via inhibition of Akt/NF-κB and MAPKs/AP-1 pathways and activation of PKA/CREB pathway in lipopolysaccharide …

D Zhao, SH Kwon, YS Chun, MY Gu, HO Yang - Neurochemical Research, 2017 - Springer
Microglia play a critical role in controlling the homeostasis of the brain, but over-activated
microglia secrete pro-inflammatory mediators and cytokines, which induce neuronal cell …

Evaluation of anti-inflammatory effect of fucoxanthin isolated from brown algae in lipopolysaccharide-stimulated RAW 264.7 macrophages

SJ Heo, WJ Yoon, KN Kim, GN Ahn, SM Kang… - Food and chemical …, 2010 - Elsevier
In this study, potential anti-inflammatory effect of fucoxanthin isolated from brown algae was
assessed via inhibitory effect of nitric oxide (NO) production in lipopolysaccharide (LPS) …

Fucoxanthin: A promising compound for human inflammation-related diseases

M Liu, W Li, Y Chen, X Wan, J Wang - Life sciences, 2020 - Elsevier
Fucoxanthin, a natural product of carotenoids, is a potential drug source obtained from
marine algae. The special chemical structure of fucoxanthin has equipped it with a variety of …

First evidence for the anti-inflammatory activity of fucoxanthin in high-fat-diet-induced obesity in mice and the antioxidant functions in PC12 cells

C Tan, Y Hou - Inflammation, 2014 - Springer
Obesity, characterized as a state of low-level inflammation, is a powerful determinant
influencing the development of insulin resistance and progression to type 2 diabetes. The …

Fucoxanthin, a Marine Xanthophyll Isolated From Conticribra weissflogii ND-8: Preventive Anti-Inflammatory Effect in a Mouse Model of Sepsis

J Su, K Guo, M Huang, Y Liu, J Zhang, L Sun… - Frontiers in …, 2019 - frontiersin.org
Background: Fucoxanthin (FX), a xanthophyll pigment which occurs in marine brown algae
with remarkable biological properties, has been proven to be safe for consumption by …

Fucoxanthin inhibits lipopolysaccharide-induced inflammation and oxidative stress by activating nuclear factor E2-related factor 2 via the phosphatidylinositol 3-kinase …

MB Kim, H Kang, Y Li, YK Park, JY Lee - European journal of nutrition, 2021 - Springer
Purpose Anti-inflammatory and antioxidant effects of fucoxanthin (FCX), a xanthophyll
carotenoid, have been suggested. However, underlying mechanisms are elusive. The …

Fucoxanthinol, metabolite of fucoxanthin, improves obesity-induced inflammation in adipocyte cells

H Maeda, S Kanno, M Kodate, M Hosokawa… - Marine drugs, 2015 - mdpi.com
Fucoxanthin (Fx) is a marine carotenoid found in edible brown seaweeds. We previously
reported that dietary Fx metabolite into fucoxanthinol (FxOH), attenuates the weight gain of …

Anti-inflammatory effect of fucoxanthin derivatives isolated from Sargassum siliquastrum in lipopolysaccharide-stimulated RAW 264.7 macrophage

SJ Heo, WJ Yoon, KN Kim, C Oh, YU Choi… - Food and Chemical …, 2012 - Elsevier
In this study, the anti-inflammatory effect of fucoxanthin (FX) derivatives, which was isolated
from Sargassum siliquastrum were evaluated by examining their inhibitory effects on pro …