How we detect microbes and respond to them: the Toll-like receptors and their transducers
B Beutler, K Hoebe, X Du… - Journal of Leucocyte …, 2003 - academic.oup.com
Macrophages and dendritic cells are in the front line of host defense. When they sense host
invasion, they produce cytokines that alert other innate immune cells and also abet the …
invasion, they produce cytokines that alert other innate immune cells and also abet the …
Sensing of microbial molecular patterns by Toll‐like receptors
DH Song, JO Lee - Immunological reviews, 2012 - Wiley Online Library
Toll‐like receptors (TLR s) sense structural patterns in microbial molecules and initiate
immune defense mechanisms. The structures of many extracellular and intracellular …
immune defense mechanisms. The structures of many extracellular and intracellular …
[PDF][PDF] Toll-like receptors. II. Distribution and pathways involved in TLR signalling
F Sandor, M Buc - Folia Biol (Praha), 2005 - int1.lf1.cuni.cz
The innate immune system senses invading microorganisms by a phylogenetically
conserved family of proteins–TLRs. They are expressed in several types of cells that …
conserved family of proteins–TLRs. They are expressed in several types of cells that …
[HTML][HTML] Toll-like receptors: linking innate and adaptive immunity
C Pasare, R Medzhitov - Microbes and infection, 2004 - Elsevier
Detection of and response to microbial infections by the immune system depends largely on
a family of pattern-recognition receptors called Toll-like receptors (TLRs). These receptors …
a family of pattern-recognition receptors called Toll-like receptors (TLRs). These receptors …
Toll-like receptors and microbes take aim at each other
DM Underhill - Current opinion in immunology, 2004 - Elsevier
Toll-like receptors (TLRs) are key components of effective innate immunity. As such,
pathogenic microorganisms must evade recognition by TLRs, manipulate the consequences …
pathogenic microorganisms must evade recognition by TLRs, manipulate the consequences …
Mini‐review Toll‐like receptors: networking for success
DM Underhill - European journal of immunology, 2003 - Wiley Online Library
The innate immune system is essential for host defense and is responsible for early
detection of potentially pathogenic microorganisms. Upon recognition of microbes by innate …
detection of potentially pathogenic microorganisms. Upon recognition of microbes by innate …
Toll-like receptor signalling
S Akira, K Takeda - Nature reviews immunology, 2004 - nature.com
One of the mechanisms by which the innate immune system senses the invasion of
pathogenic microorganisms is through the Toll-like receptors (TLRs), which recognize …
pathogenic microorganisms is through the Toll-like receptors (TLRs), which recognize …
Toll-like receptors and the host defense against microbial pathogens: bringing specificity to the innate-immune system
MG Netea, C Van der Graaf… - Journal of Leucocyte …, 2004 - academic.oup.com
Toll-like receptors (TLRs) have been identified as a major class of pattern-recognition
receptors. Recognition of pathogen-associated molecular patterns (PAMPs) by TLRs, alone …
receptors. Recognition of pathogen-associated molecular patterns (PAMPs) by TLRs, alone …
How important are Toll‐like receptors for antimicrobial responses?
S Carpenter, LAJ O'Neill - Cellular microbiology, 2007 - Wiley Online Library
The innate immune system is the primary line of defence against invading pathogenic
microbes. Toll‐like receptors (TLRs) are a family of membrane receptors which play a pivotal …
microbes. Toll‐like receptors (TLRs) are a family of membrane receptors which play a pivotal …
Toll-like receptors and innate immunity
R Medzhitov - Nature Reviews Immunology, 2001 - nature.com
Toll-like receptors have a crucial role in the detection of microbial infection in mammals and
insects. In mammals, these receptors have evolved to recognize conserved products unique …
insects. In mammals, these receptors have evolved to recognize conserved products unique …