Alkaloids from the roots of Sophora flavescens and their anti-tumor activity
Y Xu, X Wang, K Sa, H Li, L Chen - Fitoterapia, 2023 - Elsevier
Sophora flavescens belongs to Sophora genus of Leguminosae. Its roots are used as a
traditional Chinese medicine. In our study on Sophora flavescens roots, 3 new and 19 …
traditional Chinese medicine. In our study on Sophora flavescens roots, 3 new and 19 …
A reactive oxygen species activation mechanism contributes to Sophoridine-induced apoptosis in rat liver BRL-3A cells
M Qiu, F Shi, F Dai, R Song, S Wang, Y You… - Journal of …, 2018 - Elsevier
Ethnopharmacological relevance Sophora alopecuroides L., a traditional Chinese herb, has
been widely used to treat numerous diseases throughout China. Quinolizidine alkaloids …
been widely used to treat numerous diseases throughout China. Quinolizidine alkaloids …
d,l-Sulforaphane Induces ROS-Dependent Apoptosis in Human Gliomablastoma Cells by Inactivating STAT3 Signaling Pathway
Z Miao, F Yu, Y Ren, J Yang - International journal of molecular sciences, 2017 - mdpi.com
d, l-Sulforaphane (SFN), a synthetic analogue of broccoli-derived isomer l-SFN, exerts
cytotoxic effects on multiple tumor cell types through different mechanisms and is more …
cytotoxic effects on multiple tumor cell types through different mechanisms and is more …
Research progress of sophoridine's pharmacological activities and its molecular mechanism: an updated review
Y Chen, X Wang, D Ye, Z Yang, Q Shen… - Frontiers in …, 2023 - frontiersin.org
Background: Sophoridine, the major active constituent of Sophora alopecuroides and its
roots, is a bioactive alkaloid with a wide range of pharmacological effects, including …
roots, is a bioactive alkaloid with a wide range of pharmacological effects, including …
Solamargine upregulation of Fas, downregulation of HER2, and enhancement of cytotoxicity using epirubicin in NSCLC cells
CH Liang, LY Shiu, LC Chang… - Molecular nutrition & …, 2007 - Wiley Online Library
Nonsmall‐cell lung cancer (NSCLC) is not generally a chemosensitive tumor, and the
mechanism of resistance to the relevant anticancer drugs has not been fully elucidated …
mechanism of resistance to the relevant anticancer drugs has not been fully elucidated …
Research progress of matrine's anticancer activity and its molecular mechanism
F Chen, Y Pan, J Xu, B Liu, H Song - Journal of Ethnopharmacology, 2022 - Elsevier
Background and ethnopharmacological relevance: Matrine (MT), a type of alkaloid extracted
from the Sophora family of traditional Chinese medicine, has been documented to exert a …
from the Sophora family of traditional Chinese medicine, has been documented to exert a …
Solasodine induces apoptosis, affects autophagy, and attenuates metastasis in ovarian cancer cells
Solasodine, a steroidal alkaloid isolated from solanaceous species, exhibits anticancer
activities on several cell lines. This study aimed to explore the antitumor potential of …
activities on several cell lines. This study aimed to explore the antitumor potential of …
[HTML][HTML] Inhibiting autophagy enhances sulforaphane-induced apoptosis via targeting NRF2 in esophageal squamous cell carcinoma
Z Lu, Y Ren, L Yang, A Jia, Y Hu, Y Zhao… - … Pharmaceutica Sinica B, 2021 - Elsevier
Sulforaphane (SFN), a natural anti-tumor compound from cruciferous vegetables, has been
reported to induce protective autophagy to cancer cells, which might impair the anti-tumor …
reported to induce protective autophagy to cancer cells, which might impair the anti-tumor …
[HTML][HTML] Oxymatrine inhibits the development of non-small cell lung cancer through miR-367-3p upregulation and target gene SGK3 downregulation
Q Yu, J Luo, J Zhang, Y Chen, K Chen… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Oxymatrine (OM), an important active ingredient extracted from sophora flavescens, has
attracted more attention for its anti-tumor effect in recent years, with pronounced effects on …
attracted more attention for its anti-tumor effect in recent years, with pronounced effects on …
Inoscavin A, a pyrone compound isolated from a Sanghuangporus vaninii extract, inhibits colon cancer cell growth and induces cell apoptosis via the hedgehog …
P Qiu, J Liu, L Zhao, P Zhang, W Wang, D Shou, J Ji… - Phytomedicine, 2022 - Elsevier
Background Sanghuangporus vaninii, a large precious medicinal fungus called Sanghuang
in China, has significant antitumor activity. We previously reported that a Sanghuangporus …
in China, has significant antitumor activity. We previously reported that a Sanghuangporus …