Abstract Context Polyphyllin II (PPII) is a steroidal saponin isolated from Rhizoma Paridis. It
exhibits significant antitumor activity such as anti-proliferation and pro-apoptosis in lung …

Purpose Matrine, one of the main active components of extracts from the dry roots of
Sophora flavescens, has potent anti-tumor activity in various cancer cell lines. However, the …

Objective To study the in vitro antiproliferative effect and probable mechanism of solasonine
on human breast cancer Bcap-37 cells, meanwhile, make comparison with solamargine …

Background Lung cancer is the leading cause of cancer death worldwide, yet no effective
medication for this disease is available. Cochlioquinone B derivative (CoB1), purified from …

Abstract Background Timosaponin A3 (TA3), one of the active components of spirostanol
saponin isolated from A. asphodeloides, is widely used as an anticancer agent in a variety of …

Searching for potential anticancer agents from natural sources is an effective strategy for
developing novel chemotherapeutic agents. In this study, data supporting the in vitro and in …

Homoisoflavanone‑1 is a natural compound that may be extracted from the Chinese
medicinal herb Polygonatum odoratum, which has pronounced antioxidant activities. The …

Abstract Paris Saponin II (PSII) has been regarded as an effective and imperative
component isolated from Rhizoma Paridis saponins (RPS) and exhibited strong anti-tumor …

Abstract Background Saikosaponin d (SSd) is one of the main active triterpene saponins in
Bupleurum falcatum. It has a steroid-like structure, and is reported to have pharmacological …

When cells lose adhesion, they undergo detachment-induced apoptosis, known as anoikis.
In contrast, tumor cells acquire resistance to anoikis, enabling them to survive, even after …