Chronic inflammation is associated with a broad spectrum of neurodegenerative diseases of
aging. Included are such disorders as Alzheimer's disease (AD), Parkinson's disease (PD) …

Two basic discoveries spurred research into inflammation as a driving force in the
pathogenesis of Alzheimer's disease (AD). The first was the identification of activated …

This review reports correlations between four independent fields related to inflammation and
Alzheimer disease: fundamental pathology, epidemiology, transgenic animal studies and …

Two basic discoveries have spurred research into inflammation as a driving force in the
pathology of Alzheimer disease (AD). The first was the identification of activated microglia in …

Inflammation is characteristic of a broad spectrum of neurodegenerative diseases. These
include Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases, amyotrophic lateral …

In Alzheimer's disease (AD) there is increasing evidence that neurotoxicity is mediated by
CNS inflammatory processes. These processes involve activation of microglia by amyloid-β …

Inflammation is characteristic of neurodegenerative diseases of aging. Neuropathological
evidence of activated microglia and activated astrocytes in lesioned areas, combined with …

Systemic inflammation, represented in large part by the production of pro-inflammatory
cytokines, is the response of humans to the assault of the non-self on the organism. Three …

In 1990 it was reported that individuals receiving NSAIDs (non-steroidal anti-inflammatory
drugs) showed a markedly reduced prevalence of Alzheimer's disease (AD) compared to the …

Inflammation is a physiological process that repairs tissues in response to endogenous or
exogenous aggressions. Nevertheless, a chronic state of inflammation may have detrimental …