Introduction: In chronic hepatitis C-virus infection the possible role of gene variants encoding
cytokines has become the focus of interest. Aim: The aim of the study was to investigate the …

Single nucleotide polymorphisms (SNPs) in the proximity of the interleukin-28B (IL28B)
gene can predict spontaneous resolution of hepatitis C virus (HCV) infection and response …

Methods A total of 294 patients, 152 of whom had chronic hepatitis B, 59 of whom had
chronic hepatitis C, and 83 of whom had liver biopsy for different clinical indications, were …

Background: Host genetic factors can affect the progress of hepatitis-C virus (HCV) infection.
Interleukin-28B (IL28B) single nucleotide polymorphisms may play an important role in the …

Materials and Methods: The study group consisted of 18 HCV infection, who were treated
with pegylated interferon alfa (Peg-IFN-α) and ribavirin in last one year at a tertiary centre at …

A hepatite C, doença causada pelo vírus da hepatite C (HCV), é comumente assintomática,
apresenta elevada taxa de cronicidade e pode evoluir para cirrose e carcinoma …

OBJECTIVE The study was aimed to evaluate the specificity, cost and turnaround time of
three different techniques that can be used for analyzing the single nucleotide polymorphism …

Background. The prognosis concerning the treatment of patients with chronic hepatitis C
(CHC) is closely related to the genotype of the virus as well as to the factors dependent on …

Objective. Several studies recently revealed that single nucleotide polymorphisms (SNPs) in
the interleukin28B (IL28B) region are associated with the response to pegylated interferon …

Objectives: Describe the prevalence of IL28-B SNP among Brazilian patients and discuss it
possible clinical implications. Material & Methods: Frozen samples (-80C) from 500 HCV …