The effect of selenium on chemical carcinogenicity in the rat

WK Johnston - 1973 - ir.library.oregonstate.edu
One hundred and fifty-one weanling rats of both sexes were fed control diets or diets
containing 160 ppm diethylnitrosamine (DEN) or 150 ppm N-2-fluorenyl-acetamide (FAA) …

Effect of an inorganic and organic form of dietary selenium on the promotional stage of mammary carcinogenesis in the rat

HJ Thompson, LD Meeker, S Kokoska - Cancer research, 1984 - AACR
The relative effectiveness of either sodium selenite or selenomethionine in the inhibition of
mammary carcinogenesis was studied in virgin female Sprague-Dawley rats. In one …

Relationship of dietary selenium concentration; chemical cancer induction; and tissue concentration of selenium in rats

JR Harr, JH Exon, PH Weswig, PD Whanger - Clinical toxicology, 1973 - Taylor & Francis
METHODS Eighty female OSU-brown rats were weaned at 35 days of age and didded into
four groups of 20 each. The 40 rats in Groups I and XI were born from parents reared on the …

Effects of selenium supplementation on hepatocarcinogenesis in rats

TM Aquino, EA Porta, HM Sablan, RD Dorado - 1985 - Taylor & Francis
Four groups of weanling male Wistar rats (Groups A—D) received diethylnitrosamine (DEN,
40 ppm) in their drinking water for four weeks; after a recovery period of two weeks, they …

Selenium interactions with carcinogens

PD Whanger - Toxicological Sciences, 1983 - academic.oup.com
Abstract Selenium Interactions with Carcinogens. Whanger, PD (1983). Fundam. Appl
Toxicol 3: 424–430. Although selenium was once considered to be a toxic, undesirable and …

Selenium as an anticarcinogen

HJ Thompson - Journal of Agricultural and Food Chemistry, 1984 - ACS Publications
Studies in Mice. Selenium has been reported to reduce the incidence of mammary tumors
induced by mammary tumor virus in C3H/St female mice (Schrauzer and Ischmael, 1974; …

The influence of dietary selenium on colon, pancreas, and skin tumorigenesis

DF Birt, PM Pour, JC Pelling - Selenium in biology and medicine, 1989 - Springer
The influence of dietary selenium on experimental carcinogenesis has been extensively
investigated in the mammary glands of mice and rats (reviewed by Medina 1986). Most …

Effect of dietary selenium levels on methylbenzylnitrosamine-induced esophageal cancer in rats

KM Nauss, D Bueche, N Soule, P Fu, K Yew… - Cancer letters, 1986 - Elsevier
Abstract Male Sprague-Dawley rats fed selenium deficient diets received either 0 ppm, 0.15
ppm or 4.0 ppm selenium in the drinking water. Animals were treated with …

Perspectives in metal carcinogenesis. I. Selenium.

L Fishbein - Archiv fur Geschwulstforschung, 1986 - europepmc.org
This review has focused primarily on the sources of exposure to selenium and its role as an
antioxidant as well as its anticarcinogenic and antimutagenic properties. Selenium is an …

The chemopreventive role of selenium in carcinogenesis

C Ip - Journal of the American College of Toxicology, 1986 - journals.sagepub.com
HERE IS INCREASING evidence in the literature that selenium supplementation can protect
labora-T tory animals against preneoplastic lesion development or tumorigenesis induced …