Objective: Simulations of oxygen delivery by a three‐dimensional network of microvessels in
rat cerebral cortex were used to examine how the distribution of partial pressure of oxygen …

Advanced imaging techniques have made available extensive three-dimensional
microvascular network structures. Simulation of oxygen transport by such networks requires …

A compartmental model is formulated for oxygen transport in the cerebrovascular bed of the
brain. The model considers the arteriolar, capillary and venular vessels. The vascular bed is …

Using modified oxygen needle microelectrodes and intravital videomicroscopy,
measurements were made of tissue oxygen tension (PO2) profiles near cortical arterioles …

To estimate the magnitude of hyperemia necessary to support oxidative metabolism in the
cerebral cortex during functional activation, a mathematical model of O2 transport from …

The effect of chronic hypobaric hypoxia (28 days, 455 Torr) on the organization of brain
vessels was studied in Balb/c mice. In comparison to age-matched controls kept at sea level …

In the present study, we have measured partial pressure of oxygen (pO 2) profiles through
rat brain slices before and after periods of hypoxia (5 and 10 min) to determine its effect on …

The three-dimensional spatial arrangement of the cortical microcirculatory system is critical
for understanding oxygen exchange between blood vessels and brain cells. A three …

The oxygen exchange and correlation between the cerebral blood flow (CBF) and cerebral
metabolic rate of oxygen consumption (CMRO2) in the cortical capillary levels for normal …

The purpose of this study is to determine when and where the brain microvasculature
changes its network in response to chronic hypoxia. To identify the hypoxia-induced …