Alzheimer disease (AD) is an age-related neurodegenerative disorder, characterized
histopathologically by the presence of senile plaques (SP), neurofibrillary tangles and …

As a fully differentiated organ, our brain is very sensitive to cumulative oxidative damage of
proteins, lipids, and DNA occurring during normal aging because of its high energy …

With the increasing average life span of humans and with decreasing cognitive function in
elderly individuals, age-related cognitive disorders including dementia have become a …

Alzheimer's disease (AD) exhibits extensive oxidative stress throughout the body, being
detected peripherally as well as associated with the vulnerable regions of the brain affected …

Mitochondria play a pivotal role in bioenergetics and respiratory functions, which are
essential for the numerous biochemical processes underpinning cell viability. Mitochondrial …

In this paper, we discuss the interplay between beta‐amyloid (Aβ) peptide, Tau fragments,
oxidative stress, and mitochondria in the neuronal model of cerebellar granule neurons …

Mitochondrial dysfunction is involved in Alzheimer's disease (AD) pathogenesis.
Mitochondria have their own genetic material; however, most of their proteins (∼ 99%) are …

Although the basis of Alzheimer's disease (AD) etiology remains unknown, oxidative stress
(OS) has been recognized as a prodromal factor associated to its progression. OS refers to …

Being major sources of reactive oxygen species (ROS), mitochondrial structures are
exposed to high concentrations of ROS and might therefore be particularly susceptible to …

Alzheimer disease (AD) is a neurodegenerative disease with many known pathological
features, yet there is still much debate into the exact cause and mechanisms for progression …