The use of 145 digoxin and digitoxin assays was studied in a teaching hospital to determine
if performance of assays was appropriate and therapeutically beneficial. Patient charts (121) …

Abstract Evaluation of commercial kits (3H and 125I digoxin) for the radioimmunoassay of
digoxin showed that different normal plasma samples yielded significantly different standard …

The appropriateness of requests by physicians for serum digoxin measurements (SDMs)
and the appropriateness of responses by physicians to a reported SDM were evaluated with …

Background: Digoxin remains a commonly prescribed medication for the treatment of
congestive cardiac failure or atrial tachyarrhythmias. Its utility is offset by its narrow …

The criteria which a drug must fulfil before it can be said that it may be worthwhile making
regular plasma concentration measurements of that drug in monitoring therapy are …

Methods for testing digoxin bioavailability were compared in single-dose crossover studies
using eight healthy male subjects. Digoxin (0.75 mg) was given by intravenous infusion …

To study the appropriateness of phlebotomy for digoxin therapeutic drug monitoring (TDM)
in outpatients, we conducted a retrospective chart review, a computer search of all previous …

The properties of the widely used TDX Analyzer and recently developed OPUS
Immunoassay System were compared using 403 serum specimens taken from patients who …

During 1966 to 1968, 64 of 459 (13.9%) prospectively monitored, digoxin‐treated patients at
Massachusetts General Hospital suffered adverse reactions to the drug. Measurements of …

The concentrations of digoxin in plasma and urine samples obtained from three healthy
male volunteers, who received 1.2 mg of labeled digoxin perorally and intravenously, were …