A concurrent audit was made of 92 patients with plasma or serum digoxin levels of 3.0 ng/ml
or more. Evidence of digoxin toxicity was present in 44 of these patients, and premature …

1. Compliance with digoxin therapy has been assessed in a group of fifty patients receiving
the drug in general practice but not attending hospital. 2. Compliance was estimated by …

A specific method for the quantitation of digoxin in serum has been developed and applied
to determination of drug concentrations in serum from digitalized patients. One ml of the …

The ability to precisely predict serum digoxin concentrations using 12 published methods in
a group of 85 patients was undertaken. Two methods of estimating creatinine clearance and …

There are many disease states in the elderly that mandate the use of drugs with extremely
narrow therapeutic indexes and potentially fatal toxicity. Digoxin is one example of such …

The bioavailability of single doses from 4 randomly selected lots of digoxin from a single
manufacturer that were recently marketed in the United States was compared. In a crossover …

OBJECTIVE: TO assess the ability to modify physicians' use of serum digoxin assays in a
sustained fashion through (1) an educational intervention by a clinical pharmacist, and (2) …

Using the radioimmunoassay technique for measuring serum digoxin, it was found that
patients who were given 0.25 mg. digoxin orally per day had a mean serum level of …

A high-performance liquid chromatographic (HPLC) procedure has been developed for the
analysis of digoxin in plasma at therapeutic concentrations. The assay method provides …

Aim: To evaluate the proportion of inappropriate digoxin level determinations. Methods: We
performed a retrospective analysis of 210 randomly selected digoxin plasma level …