Background Serum digoxin concentrations (SDCs) are frequently sampled before
completion of drug distribution. If elevated, these concentrations may be misinterpreted …

1. We have studied the absolute bioavailability of three oral formulations of digoxin, 1.0 mg,
in 12 young healthy volunteers in a four way randomised cross‐over study using an …

Everyday physical activity previously has been shown to affect serum digoxin
concentrations. Standardized rest in the supine position increases outpatient serum digoxin …

Digoxin-containing sera from 86 patients were analyzed for this drug by bioassay and
radioimmunoassay. Each serum was analyzed in duplicate by six procedures: inhibition of …

This method for assaying digoxin in serum with improved specificity combines small-column
extraction of serum," high-performance" liquid chromatography, and RIA of the eluted …

The usefulness of measuring plasma digoxin concentrations in the diagnosis of digoxin
toxicity has been assessed in 83 in-patients. The mean plasma digoxin concentration in …

Summary 37 patients on maintenance digoxin therapy were observed in hospital over an 8
day period. From day 1 to day 8 measurements of plasma digoxin and serum creatinine …

Digoxin is an important drug in the treatment of patients with either congestive heart failure
or atrial arrhythmia. Because of its narrow therapeutic range, digoxin serum concentrations …

Digoxin usage and toxicity were compared in a prospective group of patients who were
monitored by a pharmacist and a retrospective group for which there was no pharmacist …

A direct and objective method of measuring compliance to medication is presented. Digoxin
is used as a marker in capsules of either gemfibrozil or placebo with a minimal dose of 4.4 …