Abstract Fatigue related to Multiple Sclerosis (MS) is considered a multidimensional
symptom, manifesting in several dimensions such as physical, cognitive, and psychosocial …

Background Fatigue is a complex and disabling symptom of Multiple Sclerosis (MS);
however, there is conflicting evidence of the relationship between fatigue and clinical …

Although fatigue is common among multiple sclerosis (MS) patients, evaluation of this
symptom is difficult due to the subjectivity and variability of the complaint. We proposed the …

Purpose. To determine the reproducibility, responsiveness and concurrent validity of Dutch
versions of the Fatigue Severity Scale (FSS), Modified Fatigue Impact Scale (MFIS), and …

Background: Damage of different brain structures has been related to fatigue. Alternatively,
functional alterations of central nervous system (CNS) cells by the inflammatory milieu within …

Objectives: Fatigue is one of the most common, yet poorly defined, disabling symptoms in
patients with multiple sclerosis (MS). To delineate more clearly the frequency and type of …

Background: As a symptom of multiple sclerosis (MS), fatigue is difficult to manage because
of its unknown etiology, the lack of efficacy of the drugs tested to date and the absence of …

Concept: Fatigue is a major concern for patients with multiple sclerosis (MS). A clear
definition of MS-related fatigue is a prerequisite for appropriate instruments for fatigue …

Fatigue in multiple sclerosis is a key symptom associated with work-related problems and
poor quality of life outcomes. The five-item Modified Fatigue Impact Scale is a brief self …

Background: Fatigue is the most commonly reported symptom in multiple sclerosis (MS).
Purpose: This brief narrative review addresses the clinical features, pathophysiology, and …