Colorectal cancer (CRC) is a disease with a major worldwide burden. It is the fourth most
frequently diagnosed malignancy in both sexes with almost 1 million people developing …

Colorectal cancer is a multifactorial disease. It is the third most frequently diagnosed cancer,
and the second most common cause of cancer-related deaths worldwide. The etiology of …

The colon and rectum comprise the final portion of the human digestive tract, commencing at
the ileocecal valve that marks the end of the small intestine, terminating at the anus, and …

After several decades of modest progress in the management of colorectal cancer, the
recent identification of colorectal cancer genes, increased understanding of colorectal …

Colorectal cancer (CRC) has a great impact on the world population. With increasing
frequency, CRC is described according to the presenting phenotype, based on its molecular …

Colorectal cancer (CRC) is a common malignancy and remains a formidable health burden
in the world. Surgery is the cornerstone for curative treatment, and surgical technique has …

Colon cancer is the third most common cancer globally. The risk of developing colon cancer
is influenced by a number of factors that include age and diet, but is primarily a genetic …

The process of development of colorectal cancer involves interactions between the genome
(the genetic components) of the colorectal epithelial cell and its environment. 1 These …

Molecular genetic analysis is an integral part of colorectal cancer (CRC) management. The
choice of systemic therapy for CRC is largely based on the results of tumor molecular …

The development of personalised therapy and mechanism‐targeted agents in oncology
mandates the identification of the patient populations most likely to benefit from therapy. This …