Cancer stem cells (CSCs) are rare, tumour-initiating cells that exhibit stem cell properties:
capacity of self-renewal, pluripotency, highly tumorigenic po tential, and resistance to …

Accumulating evidence has shown that cancer stem cells (CSCs), the cancer cells that have
long-term proliferative potential and the ability to regenerate tumors with phenotypically …

Simple Summary Cancer stem cells (CSCs) in breast cancer have been identified for almost
two decades. Many outstanding discoveries have established the important functions of …

Breast cancer is marked as one of the leading causes of malignancy-related morbidities
worldwide. In spite of aggressive interventions, the inevitability of relapse and metastasis …

There is increasing evidence for the cancer stem cell hypothesis, which holds that cancers
are driven by a cellular subcomponent that has stem cell properties, that is, self-renewal …

Breast cancer stem cells (BCSCs) represent a distinct subpopulation of cells with the ability
to self-renewal and differentiate into phenotypically diverse tumor cells. The involvement of …

Breast cancer stem cells (BCSC) have been implicated in tumor initiation, progression,
metastasis, recurrence, and resistance to therapy. The origins of BCSCs remain …

Breast cancers have been increasingly recognized as malignancies displaying frequent
inter-and intra-tumor heterogeneity. This heterogeneity is represented by diverse subtypes …

Both hereditary and sporadic breast cancer are suggested to develop from a stem cell
subcomponent retaining most key stem cell properties but with dysregulation of self-renewal …

Breast cancer is a public health problem both in developing and developed countries. The
breast cancer stem cell (BCSC) hypothesis has grown in the cancer research community …