Aquaporins in the brain: from aqueduct to “multi-duct”
J Badaut, JF Brunet, L Regli - Metabolic Brain Disease, 2007 - Springer
The aquaporin channel family was first considered as a family of water channels, however it
is now clear that some of these channels are also permeable to small solutes such glycerol …
is now clear that some of these channels are also permeable to small solutes such glycerol …
H uman and mouse cortical astrocytes differ in aquaporin‐4 polarization toward microvessels
Abstract Aquaporin‐4 (AQP4), the predominant water channel in the brain, is expressed in
astrocytes and ependymal cells. In rodents AQP4 is highly polarized to perivascular …
astrocytes and ependymal cells. In rodents AQP4 is highly polarized to perivascular …
Regulation of water permeability through aquaporin-4
Y Yukutake, M Yasui - Neuroscience, 2010 - Elsevier
Aquaporin-4 (AQP4) is a predominant water channel protein in mammalian brains that is
distributed with the highest density in the perivascular and subpial astrocyte end-feet. AQP4 …
distributed with the highest density in the perivascular and subpial astrocyte end-feet. AQP4 …
Functional and molecular interactions between aquaporins and Na, K-ATPase
NB Illarionova, E Gunnarson, Y Li, H Brismar, A Bondar… - Neuroscience, 2010 - Elsevier
The water channel aquaporin 4 (AQP4) is abundantly expressed in astrocytes and provides
a mechanism by which water permeability of the plasma membrane can be regulated …
a mechanism by which water permeability of the plasma membrane can be regulated …
Distribution and possible roles of aquaporin 9 in the brain
J Badaut, L Regli - Neuroscience, 2004 - Elsevier
Aquaporin 9 (AQP9) is a member of the aquaporin channel family involved in water flux
through plasma membranes and exhibits the distinct feature of being also permeable to …
through plasma membranes and exhibits the distinct feature of being also permeable to …
Expression of the astrocyte water channel aquaporin-4 in the mouse brain
Aquaporin-4 (AQP4) is a bidirectional water channel that is found on astrocytes throughout
the central nervous system. Expression is particularly high around areas in contact with …
the central nervous system. Expression is particularly high around areas in contact with …
Regulation of brain aquaporins
M Zelenina - Neurochemistry international, 2010 - Elsevier
Three aquaporins are expressed in the brain. AQP4, the predominant brain water channel,
is expressed in astrocyte endfeet facing brain capillaries, perisynaptic spaces, and nodes of …
is expressed in astrocyte endfeet facing brain capillaries, perisynaptic spaces, and nodes of …
In vivo expression of aquaporin‐4 by reactive microglia
M Tomás‐Camardiel, JL Venero… - Journal of …, 2004 - Wiley Online Library
Abstract Aquaporin‐4 (AQP4) is the most abundant aquaporin in the brain and it is widely
accepted that this AQP is solely expressed by astrocytes and ependymal cells. AQP4 is …
accepted that this AQP is solely expressed by astrocytes and ependymal cells. AQP4 is …
The aquaporin-4 water channel as a potential drug target in neurological disorders
AS Verkman, AJ Smith, P Phuan… - Expert opinion on …, 2017 - Taylor & Francis
ABSTRACT Introduction: Aquaporin-4 (AQP4) is a water transporting protein expressed at
the plasma membrane of astrocytes throughout the central nervous system (CNS). Analysis …
the plasma membrane of astrocytes throughout the central nervous system (CNS). Analysis …
Anchoring of aquaporin-4 in brain: molecular mechanisms and implications for the physiology and pathophysiology of water transport
M Amiry-Moghaddam, DS Frydenlund, OP Ottersen - Neuroscience, 2004 - Elsevier
Astrocytes show an enrichment of aquaporin-4 (AQP4) in those parts of the plasma
membrane that are apposed to pial or perivascular basal laminae. This observation begged …
membrane that are apposed to pial or perivascular basal laminae. This observation begged …