Aquaporins (AQP) constitute an evolutionarily conserved family of integral membrane water
transport channel proteins. Previous studies indicate that AQP1 is expressed exclusively in …

Astrocytes show an enrichment of aquaporin-4 (AQP4) in those parts of the plasma
membrane that are apposed to pial or perivascular basal laminae. This observation begged …

Aquaporin-4 (AQP4) is the major water channel in the CNS. Its expression at fluid-tissue
barriers (blood–brain and brain–cerebrospinal fluid barriers) throughout the brain and spinal …

Aquaporin 9 (AQP9) is a recently cloned water channel that is permeable to
monocarboxylate, glycerol and urea. In rat, AQP9 has been found in testis and liver as well …

Aquaporin-9 (AQP9) is a new member of the aquaporin family of water-selective channels
mainly expressed in liver and testis, presenting the characteristic of also being permeable to …

Cerebral edema plays a central role in the pathophysiology of many diseases of the central
nervous system (CNS) including ischemia, trauma, tumors, inflammation, and metabolic …

The main water channel of the brain, aquaporin-4 (AQP4), is one of the classical water-
specific aquaporins. It is expressed in many epithelial tissues in the basolateral membrane …

Membrane water transport is critically involved in brain volume homeostasis and in the
pathogenesis of brain edema. The cDNA encoding aquaporin-4 (AQP4) water channel …

In this review, we have tried to summarize most available data dealing with the aquaporin
(AQP) family of water channels in the CNS. Two aquaporins have been identified so far in …

Abstract Aquaporin‐4 (AQP4), a predominant water channel of the brain, mediates
transmembrane water movement at the blood–brain barrier and brain–cerebrospinal fluid …