Aquaporin 4 changes in rat brain with severe hydrocephalus
X Mao, TL Enno, MR Del Bigio - European Journal of …, 2006 - Wiley Online Library
Hydrocephalus is characterized by impaired cerebrospinal fluid (CSF) flow with enlargement
of the ventricular cavities of the brain and progressive damage to surrounding tissue. Bulk …
of the ventricular cavities of the brain and progressive damage to surrounding tissue. Bulk …
Aquaporins: role in cerebral edema and brain water balance
The regulation of water balance in the brain is crucial. A disruption in this equilibrium causes
an increase in brain water content that significantly contributes to the pathophysiology of …
an increase in brain water content that significantly contributes to the pathophysiology of …
Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema
AS Thrane, PM Rappold, T Fujita… - Proceedings of the …, 2011 - National Acad Sciences
Aquaporin-4 (AQP4) is a primary influx route for water during brain edema formation. Here,
we provide evidence that brain swelling triggers Ca2+ signaling in astrocytes and that …
we provide evidence that brain swelling triggers Ca2+ signaling in astrocytes and that …
Identification and molecular mechanisms of the rapid tonicity-induced relocalization of the aquaporin 4 channel
The aquaporin family of integral membrane proteins is composed of channels that mediate
cellular water flow. Aquaporin 4 (AQP4) is highly expressed in the glial cells of the central …
cellular water flow. Aquaporin 4 (AQP4) is highly expressed in the glial cells of the central …
Aquaporin-4 water channel protein in the rat retina and optic nerve: polarized expression in Müller cells and fibrous astrocytes
The water permeability of cell membranes differs by orders of magnitude, and most of this
variability reflects the differential expression of aquaporin water channels. We have recently …
variability reflects the differential expression of aquaporin water channels. We have recently …
AQP4 gene deletion in mice does not alter blood–brain barrier integrity or brain morphology
S Saadoun, MJ Tait, A Reza, DC Davies, BA Bell… - Neuroscience, 2009 - Elsevier
The glial cell water channel aquaporin-4 (AQP4) plays an important role in brain edema,
astrocyte migration, and neuronal excitability. Zhou et al.[Zhou J, Kong H, Hua X, Xiao M …
astrocyte migration, and neuronal excitability. Zhou et al.[Zhou J, Kong H, Hua X, Xiao M …
Aquaporin‐4 and epilepsy
Recent studies have implicated glial cells in modulation of synaptic transmission, so it is
plausible that glial cells may have a functional role in the hyperexcitability characteristic of …
plausible that glial cells may have a functional role in the hyperexcitability characteristic of …
[HTML][HTML] Impaired olfaction in mice lacking aquaporin-4 water channels
Abstract Aquaporin-4 (AQP4) is a water-selective transport protein expressed in glial cells
throughout the central nervous system. AQP4 deletion in mice produces alterations in …
throughout the central nervous system. AQP4 deletion in mice produces alterations in …
Altered waste disposal system in aging and Alzheimer's disease: focus on astrocytic aquaporin-4
M Valenza, R Facchinetti, L Steardo… - Frontiers in …, 2020 - frontiersin.org
Among the diverse cell types included in the general population named glia, astrocytes
emerge as being the focus of a growing body of research aimed at characterizing their …
emerge as being the focus of a growing body of research aimed at characterizing their …
Evidence that pericytes regulate aquaporin-4 polarization in mouse cortical astrocytes
GA Gundersen, GF Vindedal, Ø Skare… - Brain Structure and …, 2014 - Springer
Abstract Aquaporin-4 (AQP4) water channels are concentrated in astrocytic endfoot
membranes at the brain–blood and brain–cerebrospinal fluid interfaces. The mechanisms …
membranes at the brain–blood and brain–cerebrospinal fluid interfaces. The mechanisms …