Objective Gemcitabine is the first-line drug for chemotherapy of pancreatic cancer. However,
owing to the inherent and acquired resistance, gemcitabine does not change obviously the …

Objective To explore the core mechanism of long non-coding RNA (lncRNA) growth arrest-
specific transcript 5 (GAS5) in the regulation of multidrug resistance of pancreatic cancer …

Dysregulated long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) mediating
chemotherapeutic drug effects and metastasis in pancreatic cancer (PC) are key reasons for …

The acquisition of drug resistance is a major hurdle for effective cancer treatment. Although
several efforts have been made to overcome drug resistance, the underlying mechanisms …

Long noncoding RNA growth-arrest-specific transcript 5 (GAS5) has been proved to play a
crucial role in cancer chemoresistance. However, the function of GAS5 and its underlying …

Purpose Bladder cancer is the most general malignant cancer in genitourinary system, more
than 90% of BCs are bladder transitional cell carcinomas (BTCC). This study aimed to …

OBJECTIVE: In this study, we investigated the association between lncRNA GAS5 and
cisplatin (DDP) resistance in NSCLC and further studied the regulative effect of GAS5 on …

OBJECTIVE: GAS5 is a tumor suppressive lncRNA that is downregulated in gastric cancer.
In this study, we firstly investigated whether epigenetic regulation contributed to GAS5 …

The growth arrest-specific transcript 5 (GAS5) is a> 200-nt lncRNA molecule that regulates
several cellular functions, including proliferation, apoptosis, invasion and metastasis, across …

Objective The long non-coding RNA Growth-arrest-specific transcript 5 (GAS5) has been
extensively linked with the ability of cancer cells to resist chemotherapeutic interventions …