Downregulation of LncRNA GAS5 promotes liver cancer proliferation and drug resistance by decreasing PTEN expression

C Wang, S Ke, M Li, C Lin, X Liu, Q Pan - Molecular Genetics and …, 2020 - Springer
Accumulating evidence has shown that the long noncoding RNAs (lncRNAs) play a crucial
role in the regulation of hepatocellular carcinoma (HCC) progression and drug resistance. In …

[HTML][HTML] LncRNA GAS5 enhances tumor stem cell-like medicated sensitivity of paclitaxel and inhibits epithelial-to-mesenchymal transition by targeting the miR-18a-5p …

TT Lu, X Tao, HL Li, L Gai, H Huang… - Asian journal of …, 2022 - journals.lww.com
The onset of prostate cancer (PCa) is often hidden, and recurrence and metastasis are more
likely to occur due to chemotherapy resistance. Herein, we identified downregulated long …

[HTML][HTML] Long noncoding RNA GAS5 modulates α-Solanine-induced radiosensitivity by negatively regulating miR-18a in human prostate cancer cells

J Yang, T Hao, J Sun, P Wei, H Zhang - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Radiotherapy is an adjuvant treatment of surgery in prostate cancer, while radioresistance
has been the challenge of treatment. It has been reported that α-Solanine exhibits anti …

[HTML][HTML] Long non-coding RNA GAS5 inhibits DDP-resistance and tumor progression of epithelial ovarian cancer via GAS5-E2F4-PARP1-MAPK axis

X Long, K Song, H Hu, Q Tian, W Wang, Q Dong… - Journal of Experimental …, 2019 - Springer
Background Epithelial ovarian cancer (EOC) is the malignant tumor of the female
reproductive system with the highest fatality rate. Tolerance of chemotherapeutic drugs like …

[PDF][PDF] LncRNA GAS5 affects epithelial-mesenchymal transition and invasion of breast cancer cells by regulating miR-216b.

Y Li, XB Guo, YH Wei - European Review for Medical & …, 2020 - europeanreview.org
OBJECTIVE: To study the mechanism of lncRNA GAS5 affecting epithelial-mesenchymal
transition and invasion of breast cancer cells by regulating miR-216b. PATIENTS AND …

Long noncoding RNA GAS5, which acts as a tumor suppressor via microRNA 21, regulates cisplatin resistance expression in cervical cancer

Q Wen, Y Liu, H Lyu, X Xu, Q Wu, N Liu, Q Yin… - International Journal of …, 2017 - ijgc.bmj.com
Objectives The aims of this study were to investigate the functions of GAS5 as a tumor
suppressor in cervical cancer and explore the mechanism. Methods The expression of …

Long non-coding RNA GAS5 suppresses tumor progression and enhances the radiosensitivity of prostate cancer through the miR-320a/RAB21 axis

X Ma, Z Wang, H Ren, X Bao, Y Zhang… - Cancer Management …, 2020 - Taylor & Francis
Background Long non-coding RNAs (lncRNAs) function as a class of significant mediators in
prostate cancer (PCa), and this study mainly discussed the molecular mechanism of lncRNA …

GAS5 knockdown reduces the chemo-sensitivity of non-small cell lung cancer (NSCLC) cell to cisplatin (DDP) through regulating miR-21/PTEN axis

L Cao, J Chen, B Ou, C Liu, Y Zou - Biomedicine & Pharmacotherapy, 2017 - Elsevier
Non-small cell lung cancer (NSCLC), known as the most common type of lung cancer, has
caused great economic losses and brought the patients with NSCLC great suffering. The …

[HTML][HTML] The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with …

S Dong, X Qu, W Li, X Zhong, P Li, S Yang… - Journal of hematology & …, 2015 - Springer
Background Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are
approved for patients with recurrent non-small cell lung cancer (NSCLC). However, the …

Long non-coding RNA GAS5 inhibits migration and invasion in gastric cancer via interacting with p53 protein

Y Liu, L Yin, C Chen, X Zhang, S Wang - Digestive and Liver Disease, 2020 - Elsevier
Background The rapid progress of gastric cancer (GC) is mainly due to metastasis. Long non-
coding RNA (lncRNA) GAS5 has been identified as a tumor suppressor in numerous …