Background: Long non-coding RNA (lncRNAs) play critical roles in the development of
cancers. LncRNA GAS5 was identified to be involved in tumorigenesis of several cancers …

While functional studies of long noncoding RNAs (lncRNAs) have mostly focused on how
they influence disease diagnosis and prognosis, the pharmacogenomic relevance of …

Tyrosine kinase inhibitors (TKIs) exert potent therapeutic efficacy in non-small cell lung
cancers (NSCLC) harboring epidermal growth factor receptor (EGFR) activating mutations …

Abstract MicroRNAs (miRNAs) are 21–23-nucleotide, short, non-coding RNAs that play
important roles in virtually all biological pathways in mammals and other multicellular …

The androgen receptor (AR) plays an important role in the progression of prostate cancer
and is the most important therapeutic target. However, androgen deprivation therapy will …

Purpose Clinical outcomes for advanced malignant melanoma (MM) are often poor due to
tumor invasiveness, metastasis, recurrence, and multidrug resistance. Methods We …

Intention Long noncoding RNAs, transcribed from a recently discovered class of noncoding
genes, may play a critical role in regulating cellular processes, such as cell proliferation and …

Presence of quiescent, therapy evasive population often described as cancer stem cells
(CSC) or tumor initiating cells (TIC) is often attributed to extreme metastasis and tumor …

The long non‐coding RNA GAS 5 has been reported as a tumor suppressor in many
cancers. However, its functions and mechanisms remain largely unknown in esophageal …

BACKGROUND: Hepatocellular carcinoma (HCC) is the most common solid tumor in global
range, with high degree of malignancy and poor prognosis. But the relationship between the …