Skeletal muscles in chronic obstructive pulmonary disease: deconditioning, or myopathy?

PD Wagner - Respirology, 2006 - Wiley Online Library
In recent years, COPD has become increasingly thought of as a systemic disease affecting
many tissues and organs in addition to the lungs. The skeletal muscles in particular have …

From muscle disuse to myopathy in COPD: potential contribution of oxidative stress

A Couillard, C Prefaut - European Respiratory Journal, 2005 - Eur Respiratory Soc
Evidence has been accumulating that chronic inactivity leading to muscle disuse is unlikely
to be the only explanation for the peripheral muscle dysfunction of chronic obstructive …

Skeletal muscle dysfunction in chronic obstructive pulmonary disease

M Jeffery Mador, E Bozkanat - Respiratory research, 2001 - Springer
It has become increasingly recognized that skeletal muscle dysfunction is common in
patients with chronic obstructive pulmonary disease (COPD). Muscle strength and …

Peripheral skeletal muscles and exercise performance in patients with chronic obstructive pulmonary disease.

R Gosselink, M Decramer - … for Chest Disease= Archivio Monaldi per …, 1998 - europepmc.org
Impaired exercise capacity is a common finding in chronic obstructive pulmonary disease
(COPD) patients. This reduction is not a simple consequence of airflow limitation. Peripheral …

Exercise and muscle dysfunction in COPD: implications for pulmonary rehabilitation

WDC Man, P Kemp, J Moxham, MI Polkey - Clinical science, 2009 - portlandpress.com
Skeletal muscle dysfunction in COPD (chronic obstructive pulmonary disease) patients,
particularly of the quadriceps, is of clinical interest because it not only influences the …

Pathophysiology of muscle dysfunction in COPD

J Gea, A Agustí, J Roca - Journal of applied physiology, 2013 - journals.physiology.org
Muscle dysfunction often occurs in patients with chronic obstructive pulmonary disease
(COPD) and may involve both respiratory and locomotor (peripheral) muscles. The loss of …

Factors contributing to muscle wasting and dysfunction in COPD patients

RCI Wüst, H Degens - International journal of chronic obstructive …, 2007 - Taylor & Francis
Many patients with chronic obstructive pulmonary disease (COPD) suffer from exercise
intolerance. In about 40% of the patients exercise capacity is limited by alterations in skeletal …

Muscle dysfunction associated with chronic obstructive pulmonary disease

NR Macintyre - Respiratory care, 2006 - rc.rcjournal.com
Skeletal-muscle (both respiratory and limb) abnormalities are common and can have
profound effects in patients with chronic inflammatory states such as chronic obstructive …

Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease

HC Kim, M Mofarrahi, SNA Hussain - International journal of …, 2008 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a debilitating disease characterized by
inflammation-induced airflow limitation and parenchymal destruction. In addition to …

Hypoxaemia enhances peripheral muscle oxidative stress in chronic obstructive pulmonary disease

C Koechlin, F Maltais, D Saey, A Michaud, P Leblanc… - Thorax, 2005 - thorax.bmj.com
Background: Because oxidative stress affects muscle function, the underlying mechanism to
explain exercise induced peripheral muscle oxidative stress in patients with chronic …