Effects of maternal psychological stress during pregnancy on offspring brain development: considering the role of inflammation and potential for preventive …

AM Graham, O Doyle, EL Tilden, EL Sullivan… - Biological Psychiatry …, 2022 - Elsevier
Heightened psychological stress during pregnancy has repeatedly been associated with
increased risk for development of behavior problems and psychiatric disorders in offspring …

From the womb into the world: protecting the fetal brain from maternal stress during pregnancy

MI van den Heuvel - Policy Insights from the Behavioral and …, 2022 - journals.sagepub.com
No other period in a child's life matches the speed of brain development than the first nine
months in the womb. Rapid growth goes hand in hand with enormous potential, but also with …

Brain structural and functional outcomes in the offspring of women experiencing psychological distress during pregnancy

Y Wu, J De Asis-Cruz, C Limperopoulos - Molecular Psychiatry, 2024 - nature.com
In-utero exposure to maternal psychological distress is increasingly linked with disrupted
fetal and neonatal brain development and long‐term neurobehavioral dysfunction in …

Prenatal programming of neurodevelopment: Structural and functional changes

CH Demers, Ö Aran, LM Glynn, EP Davis - Prenatal stress and child …, 2021 - Springer
Prenatal maternal stress is highly prevalent and predicts many child psychopathologies.
Here, we apply the fetal programming hypothesis as an organizational framework to address …

Altered cortical structure and psychiatric symptom risk in adolescents exposed to maternal stress in utero: A retrospective investigation

GA McQuaid, VL Darcey, MF Avalos… - Behavioural brain …, 2019 - Elsevier
Maternal exposure to stress during pregnancy is associated with increased risk for cognitive
and behavioral sequelae in offspring. Animal research demonstrates exposure to stress …

Maternal distress and offspring neurodevelopment: challenges and opportunities for pre-clinical research models

E Fitzgerald, C Parent, MZL Kee… - Frontiers in Human …, 2021 - frontiersin.org
Pre-natal exposure to acute maternal trauma or chronic maternal distress can confer
increased risk for psychiatric disorders in later life. Acute maternal trauma is the result of …

[HTML][HTML] Prospective association of maternal psychosocial stress in pregnancy with newborn hippocampal volume and implications for infant social-emotional …

NK Moog, S Nolvi, TS Kleih, M Styner, JH Gilmore… - Neurobiology of …, 2021 - Elsevier
Maternal psychosocial stress during pregnancy can impact the developing fetal brain and
influence offspring mental health. In this context, animal studies have identified the …

Prenatal stress: Effects on fetal and child brain development

A Lautarescu, MC Craig, V Glover - International review of neurobiology, 2020 - Elsevier
The impact of stress on brain health begins in the womb. Both animal and human studies
have found that prenatal maternal stress affects the brain and behavior of the offspring …

Maternal perinatal stress trajectories and negative affect and amygdala development in offspring

MC Marr, AM Graham, E Feczko… - American Journal of …, 2023 - Am Psychiatric Assoc
Objective: Maternal psychological stress during pregnancy is a common risk factor for
psychiatric disorders in offspring, but little is known about how heterogeneity of stress …

Immune alterations in the intrauterine environment shapes offspring brain development in a sex-specific manner

E Guma, MM Chakravarty - Biological Psychiatry, 2024 - Elsevier
Exposure to inflammation in utero or in early life is known to increase risk for
neuropsychiatric illness. The sources of inflammation can be varied, including acute …