Understanding the metabolic processes associated with aging is key to developing effective
management and treatment strategies for age-related diseases. We investigated the …

Comparative metabolomics analysis of biofluids could provide information about the
metabolic alterations in aging. To investigate the signature of multiple metabolic profiles …

Background Aging is characterized by derangements in multiple metabolic pathways that
progressively constrict the homeostatic reserve (homeostenosis). The signature of metabolic …

Metabolites in human biofluids document the physiological status of individuals. We
conducted comprehensive, non‐targeted, non‐invasive metabolomic analysis of urine from …

The age-associated alterations in microbiomes vary across populations due to the influence
of genetics and lifestyles. To the best of our knowledge, the microbial changes associated …

Background: The process of aging and metabolism are intricately linked, thus rendering the
identification of reliable biomarkers related to metabolism crucial for delaying the aging …

Metabolites in human biofluids reflect individual physiological states influenced by various
factors. Using liquid chromatography-mass spectrometry (LC–MS), we conducted non …

Chronological age is an important predictor of morbidity and mortality; however, it is unable
to account for heterogeneity in the decline of physiological function and health with …

Human aging is invariably accompanied by a decline in renal function, a process potentially
exacerbated by uremic toxins originating from gut microbes. Based on a registered …

The process of aging and metabolism is intimately intertwined; thus, developing biomarkers
related to metabolism is critical for delaying aging. However, few studies have identified …