Francisella tularensis is an extremely virulent facultative intracellular bacterial pathogen of
many mammalian species including mice and humans in which it causes a spectrum of …

The following study determined whether commonly available mouse strains could be used
to reveal vaccines capable of protecting against aerosol exposure to virulent type A strains …

Previous studies have shown that IFN-γ, TNF-α and NOS-2, but not B cells, are crucial for
host defense against primary systemic infection with the attenuated live vaccine strain (LVS) …

Parenteral and respiratory vaccinations with the intracellular bacterium Francisella
tularensis have been studied using the live vaccine strain (LVS) in a mouse model, and …

In order to begin understanding the immunological basis for immunity to tularemia, and to
establish a baseline for judging the efficacy of potential novel vaccines, the present study …

Francisella tularensis is a Gram-negative intracellular bacterium, and the causative agent of
tularemia. The infection can be initiated by various routes and can manifest itself in several …

BALB/c mice were immunised with inactivated Francisella tularensis live vaccine strain
(LVS) and the level of protection afforded against aerosol challenge with virulent strains of F …

Francisella tularensis (FT) has been classified by the CDC as a category A pathogen
because of its high virulence and the high mortality rate associated with infection via the …

Francisella tularensis is a zoonotic, facultative intracellular bacterial pathogen capable of
initiating infection, tularemia, via multiple routes including dermal micro-abrasions and …

Francisella tularensis can cause fatal respiratory tularemia in humans and animals and is
increasingly being isolated in the United States and several European countries. The …