We have recently reported the use of sequential simplex optimization methods to design a
medium (SOM) that overcomes the block to development beyond two cells which occurs in …

A new medium derived from the use of sequential simplex optimization methods (SOM) that
overcomes the block to development beyond two cells in vitro in embryos of the CF1 …

Culture media were developed for pronuclear-stage mouse embryos using simplex
optimization, which has the benefit of being able to optimize several components …

Considerable advances in media development for the culture of preimplantation mammalian
embryos have been made since mouse embryos were first cultured and successfully …

Simplex optimization has generated several media that have improved the development of
mouse preimplantation embryos in vitro. One objective of this study was to compare the …

The culture conditions for the development in vitro of (C57BL/6 X CBA) F2 hybrid two-cell
embryos to the blastocyst stage have been optimized. Commercially available pre-sterile …

There has been a considerable improvement in the media available for the culture of
preimplantation mouse embryos during the 40 years since mouse embryos were first …

The morphology, cleavage rate and viability of preimplantation embryos from random bred
Swiss mice were assessed after culture in different incubation volumes and embryo …

A growing number of medical, scientific and biotechnological procedures rely on culture of
mammalian preimplantation embryos. This review presents currently available data on …

Results of recent experiments indicate that the improved development of mouse embryos in
medium containing a low NaCl concentration (85 mM) or the inclusion of the organic …