Background: The benefits of treating isolated systolic hypertension (ISH) are well
established, but the most appropriate drug choice is still uncertain. Objective: The purpose of …

Background and objective: Isolated systolic hypertension (ISH) affects 10–20% of the elderly
population and is strongly related to the risk of cardiovascular events. Elevated systolic BP …

The antihypertensive efficacy and safety of amlodipine (5-10 mg once daily for 10 weeks)
was assessed in elderly patients with primary systolic hypertension (average sitting and …

Objective The prevalence of isolated systolic hypertension (ISH) is high in the elderly, and
the objective of this study was to compare the antihypertensive efficacy of olmesartan …

Abstract A 90‐day, multicenter, randomized, double‐blind, parallel‐group study was
conducted to compare the efficacy of amlodipine (once a day) with nicardipine (two to three …

Background: Some antihypertensive therapies are limited by dose-dependent adverse
effects (AEs). The angiotensin II receptor blocker valsartan has been shown to reduce blood …

Objective: The purpose of this 8-week, randomised, single-blind, parallel group, multicentre,
comparative study was to evaluate the efficacy, safety and tolerability of the dihydropyridine …

Background: Elevated systolic blood pressure is a more important risk factor for
cardiovascular and renal disease than elevated diastolic blood pressure. Isolated systolic …

Isolated systolic hypertension affects over 15% of all subjects older than 60 years. In the
elderly, systolic hypertension is the major modifiable cardiovascular risk factor. Three …

Isolated systolic hypertension affects 8% to 15% of all people older than 60 years of age. In
the elderly, systolic hypertension is the major modifiable cardiovascular risk factor. Three …