Objectives To assess the effects of empiric antibiotics with different degrees of
appropriateness based on hospital cumulative antibiograms in patients with bacteraemic …

The appropriate antibiotic treatment of patients with bacterial sepsis in the intensive care unit
(ICU) remains a challenge. Considering that current international guidelines recommend 7 …

Objectives Our primary goal was to evaluate the impact on in-hospital mortality rate of
adequate empirical antibiotic therapy, after controlling for confounding variables, in a cohort …

Sepsis is a condition that requires appropriate antibiotic treatment at the emergency
department (ED). Most previous studies conducted on inappropriate antibiotic use at the ED …

Background. Inappropriate empiric antimicrobials could be a major cause of unfavorable
mortality rates in co‐morbid patients. This study aimed to assess the prevalence and impact …

Background Studies on the effect of inadequate empirical antibiotic therapy on the outcome
of patients with systemic infection have led to inconsistent results. Methods We analysed …

Objectives: Recognition of sepsis frequently occurs in emergency departments. To evaluate
the appropriateness of empiric antibiotic use in the setting of suspected sepsis in emergency …

Purpose Fast diagnosis and initiation of appropriate antibiotic therapy is pivotal for the
survival of sepsis patients. However, most studies on suspected sepsis patients are …

The optimal approach for empirical antibiotic therapy in patients with severe sepsis and
septic shock remains controversial. A retrospective cohort study was conducted in the …

Quantifying the benefit of early antibiotic treatment is crucial for decision making and can be
assessed only in observational studies. We performed a systematic review of prospective …