Alzheimer's disease is the most prevalent type of dementia and is caused by the deposition
of extracellular amyloid‐beta and abnormal tau phosphorylation. Neuroinflammation has …

The hallmarks of Alzheimer's disease are the aggregates of amyloid-β (Αβ) peptide and tau
protein. Autophagy is one major cellular pathway leading to the removal of aggregated …

Microglia over‐activation contributes to neurodegenerative processes by neurotoxin factors
and pro‐inflammatory molecules of pro‐inflammatory processes. Mitochondrial reactive …

The autophagy process is the major cellular degradation pathway for long-lived proteins and
organelles. Dysfunction of autophagy may lead to several neurodegenerative disorders …

Autophagy is an essential cellular process that is deeply integrated with innate immune
signaling; however, studies that examine the impact of autophagic modulation in the context …

The fibrillar peptide amyloid-β (Aβ) has a chief function in the pathogenesis of Alzheimer's
disease. Interleukin 1β (IL-1β) is a key cytokine in the inflammatory response to Aβ …

Neuroinflammation is a pathological change that is involved in the progression of
Parkinson's disease. Dysfunction of chaperone-mediated autophagy (CMA) has …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by the
presence of misfolded proteins, amyloid-β (Aβ) aggregates, and neuroinflammation in the …

Neuroinflammation and autophagy dysfunction are closely related to the development of
neurodegeneration such as Parkinson's disease (PD). However, the role of autophagy in …

Autophagy, a bulk degradation of subcellular constituents, is activated in normal cell growth
and development, and represents the major pathway by which the cell maintains a balance …