Evidence-Based Neonatal Transfusion Guidelines

RK Ohls - Principles of Neonatology, 2024 - Elsevier
Pathologic anemia is defined by an inadequate red blood cell mass that fails to meet the
oxygen needs of tissues. Neonates often require red cell transfusions due to a decreased …

Red cell transfusion thresholds for preterm infants: finally some answers

EF Bell - Archives of Disease in Childhood-Fetal and Neonatal …, 2022 - fn.bmj.com
Extremely low birthweight infants become anaemic during their care in the neonatal
intensive care unit because of the physiological anaemia experienced by all newborn …

Predictive factors and practice trends in red blood cell transfusions for very-low-birth-weight infants

OA Ekhaguere, FH Morriss, EF Bell, N Prakash… - Pediatric …, 2016 - nature.com
Background: Red blood cell (RBC) transfusions in very-low-birth-weight (VLBW) infants,
while common, carry risk. Our objective was to determine clinical predictors of and trends in …

Randomized trial of liberal versus restrictive guidelines for red blood cell transfusion in preterm infants

EF Bell, RG Strauss, JA Widness, LT Mahoney… - …, 2005 - publications.aap.org
Objective. Although many centers have introduced more restrictive transfusion policies for
preterm infants in recent years, the benefits and adverse consequences of allowing lower …

A rational approach to red blood cell transfusion in the neonatal ICU

M Crowley, H Kirpalani - Current opinion in pediatrics, 2010 - journals.lww.com
This field is plagued by lack of replication, small studies and speculative findings. Hence, the
risk–benefit ratio of blood transfusions for preterms still needs adequate definition. Evidence …

Red blood cell transfusion in preterm infants: current evidence and controversies

C Howarth, J Banerjee, N Aladangady - Neonatology, 2018 - karger.com
The current evidence regarding the indication, advantages and risks of red blood cell
transfusion (RBCT) for preterm infants is discussed. This is an important area in …

Low versus high haemoglobin concentration threshold for blood transfusion for preventing morbidity and mortality in very low birth weight infants

R Whyte, H Kirpalani - Cochrane Database of Systematic …, 2011 - cochranelibrary.com
Background Infants of very low birth weight often receive multiple transfusions of red blood
cells, usually in response to predetermined haemoglobin or haematocrit thresholds. In the …

Red blood cell transfusion in preterm infants: restrictive versus liberal policy

G Chirico, F Beccagutti, A Sorlini, M Motta… - The Journal of …, 2011 - Taylor & Francis
Preterm neonates represent a category of patients with high transfusion needs. Ideally, red
blood cells (RBC) transfusion should be tailored to the individual requirements of the single …

[HTML][HTML] Red blood cell transfusion and clinical outcomes in extremely low birth weight preterm infants

YC Wang, OW Chan, MC Chiang, PH Yang… - Pediatrics & …, 2017 - Elsevier
Background Red blood cell (RBC) transfusion is often considered a life-saving measure in
critically ill neonates. The smallest and least mature infants tend to receive the largest …

Strict red blood cell transfusion guideline reduces the need for transfusions in very‐low‐birthweight infants in the first 4 weeks of life: a multicentre trial

AM Miyashiro, N Dos Santos, R Guinsburg… - Vox …, 2005 - Wiley Online Library
Background and Objectives Very‐low‐birthweight infants are among the most heavily
transfused patients. The objective of this study was to verify if the introduction of a strict …