Metabolic profiling of serum for osteoarthritis biomarkers
Z Xiao, Z Zhang, S Huang, JR Lon, S Xie - Disease Markers, 2022 - Wiley Online Library
Osteoarthritis is a prevalent aging disease in the world, and in recent years it has shown a
trend toward younger age, which is becoming a major health problem in the world and …
trend toward younger age, which is becoming a major health problem in the world and …
Effects of long-term exercise and a high-fat diet on synovial fluid metabolomics and joint structural phenotypes in mice: an integrated network analysis
AK Hahn, A Batushansky, RA Rawle, EBP Lopes… - Osteoarthritis and …, 2021 - Elsevier
Objective To explore how systemic factors that modify knee osteoarthritis risk are connected
to 'whole-joint'structural changes by evaluating the effects of high-fat diet and wheel running …
to 'whole-joint'structural changes by evaluating the effects of high-fat diet and wheel running …
Serum metabolic signatures of four types of human arthritis
M Jiang, T Chen, H Feng, Y Zhang, L Li… - Journal of Proteome …, 2013 - ACS Publications
Similar symptoms of the different types of arthritis have continued to confound the clinical
diagnosis and represent a clinical dilemma making treatment choices with a more …
diagnosis and represent a clinical dilemma making treatment choices with a more …
Metabolomic analysis in spondyloarthritis: A systematic review
T Huang, Y Pu, X Wang, Y Li, H Yang, Y Luo… - Frontiers in …, 2022 - frontiersin.org
Spondyloarthritis (SpA) is a group of rheumatic diseases that cause joint inflammation.
Accumulating studies have focused on the metabolomic profiling of SpA in recent years. We …
Accumulating studies have focused on the metabolomic profiling of SpA in recent years. We …
Metabolomics Signature for Non‐Responders to Total Joint Replacement Surgery in Primary Osteoarthritis Patients: The Newfoundland Osteoarthritis Study
Although total joint replacement (TJR) surgery is considered as the most effective treatment
for advanced osteoarthritis (OA) patients, up to one‐third of patients reported unfavorable …
for advanced osteoarthritis (OA) patients, up to one‐third of patients reported unfavorable …
GC/TOF-MS-based metabolomic profiling in cultured fibroblast-like synoviocytes from rheumatoid arthritis
Objectives Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease
characterized by synovial inflammation and hyperplasia. Fibroblast-like synoviocytes (FLS) …
characterized by synovial inflammation and hyperplasia. Fibroblast-like synoviocytes (FLS) …
Metabolomics of synovial fluid and infrapatellar fat pad in patients with osteoarthritis or rheumatoid arthritis
P Nieminen, W Hämäläinen, J Savinainen, M Lehtonen… - Inflammation, 2022 - Springer
Osteoarthritis (OA) and autoimmune-driven rheumatoid arthritis (RA) are inflammatory joint
diseases with complex and insufficiently understood pathogeneses. Our objective was to …
diseases with complex and insufficiently understood pathogeneses. Our objective was to …
Identification of key factors in cartilage tissue during the progression of osteoarthritis using a non-targeted metabolomics strategy
S Sun, M Chen, T Zhang, Y Wang, W Shen, T Zhang… - Phenomics, 2024 - Springer
This research was to reveal the key factors in the progression of osteoarthritis (OA) using
non-targeted metabolomics and to find targeted therapies for patients with OA. Twenty-two …
non-targeted metabolomics and to find targeted therapies for patients with OA. Twenty-two …
Serum branched-chain amino acid to histidine ratio: a novel metabolomic biomarker of knee osteoarthritis
Objective There is a pressing need to develop reliable molecular biomarkers in
osteoarthritis. The aim of the study was to identify novel serum biomarkers for osteoarthritis …
osteoarthritis. The aim of the study was to identify novel serum biomarkers for osteoarthritis …
Serum metabolomic signatures for knee cartilage volume loss over 10 years in community-dwelling older adults
Osteoarthritis (OA) is the most prevalent joint disorder characterized by joint structural
pathological changes with the loss of articular cartilage as its hallmark. Tools that can predict …
pathological changes with the loss of articular cartilage as its hallmark. Tools that can predict …